MEPCE Antibodies

AND MEPCE ELISA kits, MEPCE Proteins

Many biological assays use antibodies to detect MEPCE, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MEPCE in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MEPCE antibodies...

We validate the specificity of these antibodies to MEPCE by testing them on tissues known to express MEPCE positively and negatively. Browse below to find the MEPCE antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MEPCE Infographic by Boster Bio

All MEPCE Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MEPCE Antibody

Immunofluorescence analysis of A549 cells using MEPCE antibody

Human

IF, ICC

$405
Cat # A08738
100ul

Anti-MEPCE Mouse Monoclonal Antibody [Clone ID: OTI2E7]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MEPCE (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 3 cell lines lysates by using anti-MEPCE monoclonal antibody (1:250)

Human, Mouse

$523
Cat # M08738
100 µl

MEPCE (NM_019606) Human Over-expression Lysate

Human

$628
Cat # LS056257
20 µg, 100 µg

Anti-MEPCE Antibody Picoband®

Western blot analysis of MEPCE using anti-MEPCE antibody (A08738-2)

IF analysis of MEPCE using anti-MEPCE antibody (A08738-2) and anti-Beta Tubulin antibody (M01857-3)

Flow Cytometry analysis of MCF-7 cells using anti-MEPCE antibody (A08738-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A08738-2
100 μg/vial

MEPCE Overview

Facts about 7SK snRNA methylphosphate capping enzyme.

MEPCE 3D structure. Source: alphafold

7SK snRNA methylphosphate capping enzyme (MEPCE)

S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it. .

Gene Information

Human
Gene Name:	MEPCE
Uniprot:	Q7L2J0
Entrez:	56257

Family

Belongs to:

methyltransferase superfamily

Alternative Names

BCDIN37SK snRNA methylphosphate capping enzyme; bicoid-interacting 3, homolog; Bin3 homolog; bin3, bicoid-interacting 3, homolog (Drosophila); EC 2.1.1.-; FLJ20257; methylphosphate capping enzyme

Molecular Weight

Mass (kDA):
74.355 kDA

Genomic Context


Human

Location:	7q22.1
Sequence:	7; NC_000007.14 (100428790..100434118)

Tissue Specificity

Expressed in chronic myeloid leukemia cells, adrenal gland, brain, cerebellum, kidney, lung, mammary gland and testis. Weakly or not expressed in other tissues.

Diseases

Lupus Erythematosus, Systemic

Pathways

Translation
Cell Growth
Rna Processing

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MEPCE

References

PMID: 12358911 by Rogers S.A., et al. Identification and characterization of a novel gene encoding a SEREX antigen in chronic myeloid leukaemia.

PMID: 17643375 by Jeronimo C., et al. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.