MEST Antibodies

AND MEST ELISA kits, MEST Proteins

Many biological assays use antibodies to detect MEST, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MEST in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MEST antibodies...

We validate the specificity of these antibodies to MEST by testing them on tissues known to express MEST positively and negatively. Browse below to find the MEST antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for MEST? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MEST Western Blot Guide

MEST Infographic by Boster Bio

All MEST Products

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Specificity

Applications

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Anti-MEST Antibody Picoband®

Western blot analysis of MEST using anti-MEST antibody (A07241-1)

IHC analysis of MEST using anti-MEST antibody (A07241-1)

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A07241-1
100 µg/vial

MEST (NM_002402) Human Over-expression Lysate

MEST Human Over-expression Lysates NM_002402

Human

$628
Cat # LS004232
20 µg, 100 µg

MEST Overview

Facts about Mesoderm-specific transcript homolog protein.

MEST 3D structure. Source: alphafold

Mesoderm-specific transcript homolog protein (MEST)

Gene Information

Human
Gene Name:	MEST
Uniprot:	Q5EB52
Entrez:	4232

Family

Belongs to:

AB hydrolase superfamily

Alternative Names

DKFZp686L18234; EC 3.-; mesoderm specific transcript (mouse) homolog; mesoderm specific transcript homolog (mouse); mesoderm-specific transcript homolog protein; MGC111102; MGC8703; paternally expressed gene 1; PEG1Paternally-expressed gene 1 protein

Molecular Weight

Mass (kDA):
38.83 kDA

Genomic Context


Human

Location:	7q32.2
Sequence:	7; NC_000007.14 (130486175..130506465)

Tissue Specificity

Highly expressed in hydatidiform moles, but barely expressed in dermoid cysts. Biallelic expression is detected in blood lymphocytes. Seems to imprinted in an isoform- specific manner rather than in a tissue-specific manner in lymphocytes. Isoform 1 is expressed only from the paternal allele. Isoform 2 is expressed from both the paternal allele and the maternal allele.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Benign Mixed Epithelial And Stromal Tumor Of Kidney
Edema
Auricular Swelling
Russell-silver Syndrome
Neoplasms
Uniparental Disomy
Malignant Neoplasms
Contact Dermatitis
Epilepsy
Growth Retardation
Infertility
Fetal Growth Retardation

Kidney Neoplasm
Obesity
Contact Hypersensitivity
Growth Disorders
Dermatitis, Allergic Contact
Cell Transformation, Neoplastic
Carcinoma

Pathways

Methylation
Dna Methylation
Hypersensitivity
Sensitization
Cell Proliferation
Fertilization
Spermatogenesis
Demethylation
Oocyte Growth
Metaphase
Pathogenesis
Localization
Maternal Behavior

Embryo Development
Cell Differentiation
Oogenesis
Aging
Angiogenesis
Histone Modification
Long-term Memory

PTMs

Methylation
Demethylation
Phosphorylation
Reduction

Cleavage
Glycosylation
Acetylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MEST

References

PMID: 8884280 by Nishita Y., et al. Genomic imprinting and chromosomal localization of the human MEST gene.

PMID: 9192843 by Riesewijk A.M., et al. Monoallelic expression of human PEG1/MEST is paralleled by parent- specific methylation in fetuses.