MICAL3 Antibodies

AND MICAL3 ELISA kits, MICAL3 Proteins

Many biological assays use antibodies to detect MICAL3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MICAL3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MICAL3 antibodies...

We validate the specificity of these antibodies to MICAL3 by testing them on tissues known to express MICAL3 positively and negatively. Browse below to find the MICAL3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MICAL3 Infographic by Boster Bio

All MICAL3 Products

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Anti-MICAL3 Antibody Picoband®

Western blot analysis of MICAL3 using anti-MICAL3 antibody (A08089)

Flow Cytometry analysis of U251 cells using anti-MICAL3 antibody (A08089)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A08089
100 µg/vial

MICAL3 Overview

Facts about [F-actin]-monooxygenase MICAL3.

MICAL3 3D structure. Source: alphafold

[F-actin]-monooxygenase MICAL3 (MICAL3)

Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of actin, in addition, it functions as a NADPH oxidase producing H(2)O(2).

Appears to act as Rab effector protein and plays a role in vesicle trafficking. Involved in exocytic vesicles tethering and fusion: the monooxygenase activity is required for this procedure and implicates RAB8A associated with exocytotic vesicles.

Gene Information

Human
Gene Name:	MICAL3
Uniprot:	Q7RTP6
Entrez:	57553

Family

Belongs to:

Mical family

Alternative Names

microtubule associated monoxygenase, calponin and LIM domain containing 3

Molecular Weight

Mass (kDA):
224.295 kDA

Genomic Context


Human

Location:	22q11.21
Sequence:	22; NC_000022.11 (17787649..18024561, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Nucleus. Midbody. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body. Mainly localizes in the nucleus.