Max-like protein X Antibodies

AND MLX ELISA kits, Max-like protein X Proteins

Many biological assays use antibodies to detect Max-like protein X, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Max-like protein X in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Max-like protein X antibodies...

We validate the specificity of these antibodies to Max-like protein X by testing them on tissues known to express MLX positively and negatively. Browse below to find the MLX antibody that suites your experiment. We have 9 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Max-like protein X? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MLX Western Blot Guide

MLX Infographic by Boster Bio

All MLX Products

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Specificity

Applications

Price

Anti-MLX-interacting protein/MLXIP Antibody Picoband®

Western blot analysis of MLX-interacting protein/MLXIP using anti-MLX-interacting protein/MLXIP antibody (A08709-2)

IHC analysis of MLX-interacting protein/MLXIP using anti-MLX-interacting protein/MLXIP antibody (A08709-2)

Human, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A08709-2
100 μg/vial

Anti-MLX Antibody Picoband®

Western blot analysis of MLX using anti-MLX antibody (A03087-2)

Flow Cytometry analysis of THP-1 cells using anti-MLX antibody (A03087-2)

Human, Monkey, Mouse

Flow Cytometry, WB

$370
Cat # A03087-2
100 μg/vial

Anti-MLX Antibody Picoband®

Western blot analysis of MLX using anti-MLX antibody (A03087-3)

Human

ELISA, WB

$370
Cat # A03087-3
100 μg/vial

MLX (NM_198205) Human Over-expression Lysate

MLX Human Over-expression Lysates NM_170607

Human

$628
Cat # LS006945
20 µg, 100 µg

Anti-MLX-interacting protein MLXIP Antibody

Western blot analysis of MLXIP in MCF7 cell lysate with MLXIP antibody at 1 μg/mL

Human

ELISA, WB

$481
Cat # A08709
0.1 mg

MLX interacting protein (MLXIP) (NM_014938) Human Over-expression Lysate

Human

$960
Cat # LS022877
20 µg, 100 µg

CHREBP (MLXIPL) (NM_032951) Human Over-expression Lysate

Human

$960
Cat # LS051085
20 µg, 100 µg

Anti-MLXIPL Antibody

Western blot analysis of extracts of various cell lines, using MLXIPL antibody at 1:1000 dilution

Human, Mouse

$405
Cat # A03145
100ul

MLX (NM_198205) Human Recombinant Protein

Coomassie blue staining of purified MLX protein

$1249
Cat # PROTQ9UH92
20 µg

MLX Overview

Facts about Max-like protein X.

MLX 3D structure. Source: alphafold

Max-like protein X (MLX)

Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'.

The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes.

Gene Information

Human
Gene Name:	MLX
Uniprot:	Q9UH92
Entrez:	6945

Family

Belongs to:

No superfamily

Alternative Names

BHLHD13; bHLHd13Max-like bHLHZip protein; BigMax alpha; BigMax protein; Class D basic helix-loop-helix protein 13; MAD7; MAX-like protein X; MLX; MXD7; TCFL4; TCFL4Protein BigMax; transcription factor-like 4; Transcription factor-like protein 4

Molecular Weight

Mass (kDA):
33.3 kDA

Genomic Context


Human

Location:	17q21.2
Sequence:	17; NC_000017.11 (42567060..42573203)

Subcellular Localizations

[Isoform Alpha]: Cytoplasm. Found predominantly in the cytoplasm (PubMed:10918583).; [Isoform Beta]: Cytoplasm. Found predominantly in the cytoplasm (PubMed:10918583).; [Isoform Gamma]: Nucleus. Found predominantly in the nucleus (PubMed:10918583).

Diseases

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Liver Carcinoma
Maturity Onset Diabetes Mellitus In Young
Liver Neoplasms
Malignant Neoplasms
Hepatitis
Neoplasms
Hyperglycemia
Obesity
Carcinoma
Hepatitis B

Hypoxia
Hepatoblastoma
Insulin Resistance
Hemorrhage
Liver Neoplasms, Experimental
Diabetes Mellitus, Insulin-dependent
Bleeding Tendency

Interacting Proteins

AES
GABARAPL2

Pathways

Secretion
Insulin Secretion
Coagulation
Localization
Translation
Blood Coagulation
Cholesterol Homeostasis
Hepatocyte Differentiation
Gluconeogenesis
Glucose Homeostasis
Pathogenesis
Glycolysis
Liver Development

Cell Growth
Transport
Regulation Of Gene Expression
Cell Cycle
Cell Death
Viral Replication
Cell Differentiation

PTMs

Phosphorylation
Oxidation
Carboxylation
Acetylation
Methylation

Nitrosylation
Hydroxylation
Cleavage
Glycosylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MLX

References

PMID: 10593926 by Billin A.N., et al. Mlx, a novel Max-like bHLHZip protein that interacts with the Max network of transcription factors.

PMID: 10918583 by Meroni G., et al. Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?