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- Table of Contents
Facts about Transcriptional activator MN1.
Promotes maturation and normal use of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL. Necessary for normal development of the membranous bones of the skull (By similarity).
| Human | |
|---|---|
| Gene Name: | MN1 |
| Uniprot: | Q10571 |
| Entrez: | 4330 |

| Belongs to: |
|---|
| No superfamily |

Transcriptional activator MN1
Mass (kDA):
136.001 kDA

| Human | |
|---|---|
| Location: | 22q12.1 |
| Sequence: | 22; NC_000022.11 (27748277..27801756, complement) |
Ubiquitously expressed. Highest levels in skeletal muscle.

PMID: 7731706 by Deprez R.H.L., et al. Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma.
PMID: 7731705 by Buijs A., et al. Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11.