Modulator of apoptosis 1 Antibodies

AND MOAP1 ELISA kits, Modulator of apoptosis 1 Proteins

Many biological assays use antibodies to detect Modulator of apoptosis 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Modulator of apoptosis 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Modulator of apoptosis 1 antibodies...

We validate the specificity of these antibodies to Modulator of apoptosis 1 by testing them on tissues known to express MOAP1 positively and negatively. Browse below to find the MOAP1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MOAP1 Infographic by Boster Bio

All MOAP1 Products

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Anti-MAP1 MOAP1 Antibody

Western blot analysis of MAP-1 in EL4 cell lysate with MAP-1 antibody (IN) at (A) 1, (B) 2, and (C) 4 μg/mL

Human, Mouse

ELISA, WB

$481
Cat # A08043
0.1 mg

MAP1 (MOAP1) (NM_022151) Human Recombinant Protein

Coomassie blue staining of purified MOAP1 protein

$1249
Cat # PROTQ96BY2
20 µg

MAP1 (MOAP1) (NM_022151) Human Over-expression Lysate

Human

$628
Cat # LS064112
20 µg, 100 µg

Anti-MOAP1 Antibody Picoband®

Western blot analysis of MOAP1 using anti-MOAP1 antibody (A08043-1)

IHC analysis of MOAP1 using anti-MOAP1 antibody (A08043-1)

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A08043-1
100 µg/vial

MOAP1 Overview

Facts about Modulator of apoptosis 1.

MOAP1 3D structure. Source: alphafold

Modulator of apoptosis 1 (MOAP1)

Required for passing receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.

Gene Information

Human
Gene Name:	MOAP1
Uniprot:	Q96BY2
Entrez:	64112

Family

Belongs to:

PNMA family

Alternative Names

MAP1; MAP-1PNMA4Paraneoplastic antigen Ma4; modulator of apoptosis 1; paraneoplastic antigen like 4

Molecular Weight

Mass (kDA):
39.513 kDA

Genomic Context


Human

Location:	14q32.12
Sequence:	14; NC_000014.9 (93182199..93184897, complement)

Tissue Specificity

Widely expressed, with high levels in heart and brain.

Diseases

Neoplasms
Mammary Neoplasms
Inflammation
Influenza
Cell Transformation, Neoplastic
Aortic Stiffness
Classical Swine Fever
Nervous System Disorder
Genomic Instability
Polyploidy
Tissue Adhesions
Atherosclerosis

Degenerative Polyarthritis
Paraneoplastic Syndromes
Arthritis
Vascular System Injuries
Hemorrhage
Pigmented Villonodular Synovitis

Interacting Proteins

CAMK2D
PNMA5
THOC1

Pathways

Cell Death
Cell Growth
Release Of Cytochrome C From Mitochondria
Cell Cycle
Cell Proliferation
Hyphal Growth
Programmed Cell Death
Dna Repair
Cellular Process

Pigmentation
Methylation
Germination
Regulation Of Cell Growth

PTMs

Phosphorylation

Cleavage

Ubiquitination

Research Areas

Apoptosis
MAP Kinase Signaling

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MOAP1

References

PMID: 11060313 by Tan K.O., et al. MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains.

PMID: 15949439 by Baksh S., et al. The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death.