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- Table of Contents
MPG Antibodies
AND MPG ELISA kits, MPG Proteins
Many biological assays use antibodies to detect MPG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MPG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MPG antibodies...
Designing a Western blot for MPG? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MPG Western Blot GuideMPG Infographic by Boster Bio
All MPG Products
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Specificity
Applications
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MPG Overview
Facts about DNA-3-methyladenine glycosylase.
DNA-3-methyladenine glycosylase (MPG)
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MPG |
| Uniprot: | P29372 |
| Entrez: | 4350 |
Family
| Belongs to: |
|---|
| DNA glycosylase MPG family |
Alternative Names
3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on16p; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; AAG; ADPG; anpg; APNG; CRA36.1 (3-methyl-adenine DNA glycosylase); CRA36.1; DNA-3-methyladenine glycosylase; EC 3.2.2.21; MDGalkyladenine DNA glycosylase; Mid1; N-methylpurine-DNA glycosylase, MPG; N-methylpurine-DNA glycosylasePIG16; PIG11; proliferation-inducing protein 11; proliferation-inducing protein 16
Molecular Weight
Mass (kDA):
32.869 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16p13.3 |
| Sequence: | 16; NC_000016.10 (77019..85851) |
Subcellular Localizations
Cytoplasm. Mitochondrion matrix, mitochondrion nucleoid. Nucleus.
Diseases
- Ischemia
- Infarction
- Myocardial Infarction
- Malignant Neoplasms
- Myocardial Reperfusion Injury
- Reperfusion Injury
- Neoplasms
- Myocardial Ischemia
- Albinism
- Coronary Occlusion
- Diabetes Mellitus
- Radiation Injuries, Experimental
Interacting Proteins
- HSD17B14
- PRNP
Pathways
- Dna Repair
- Innervation
- Transport
- Cell Death
- Localization
- Regeneration
- Pathogenesis
- Micturition
- Excretion
- Cell Cycle
- Mismatch Repair
- Reflex
- Vasoconstriction
PTMs
- Phosphorylation
- Methylation
- Oxidation
- Cleavage
- Reduction
- Deamination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MPG
bosterbio.com/bosterbio-gene-info-cards/MPG
References
PMID: 1924375 by Samson L., et al. Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16.
PMID: 8475094 by Vickers M.A., et al. Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere.