MPZL2 Antibodies

AND MPZL2 ELISA kits, MPZL2 Proteins

Many biological assays use antibodies to detect MPZL2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MPZL2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MPZL2 antibodies...

We validate the specificity of these antibodies to MPZL2 by testing them on tissues known to express MPZL2 positively and negatively. Browse below to find the MPZL2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MPZL2 Infographic by Boster Bio

All MPZL2 Products

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Product

Figures

Specificity

Applications

Price

EVA1 (MPZL2) (NM_005797) Human Recombinant Protein

Coomassie blue staining of purified MPZL2 protein

$1062
Cat # PROTO60487
20 µg

Anti-EVA1 (MPZL2) Mouse Monoclonal Antibody [Clone ID: OTI2C7]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MPZL2 (Right lane) cDNA for 48 hrs and lysed

Anti-MPZL2 mouse monoclonal antibody (M11230) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MPZL2

Human

IF, WB

$523
Cat # M11230
100 µl

EVA1 (MPZL2) (NM_005797) Human Over-expression Lysate

EVA1 (MPZL2) Human Over-expression Lysates NM_005797

Human

$628
Cat # LS010205
20 µg, 100 µg

Anti-MPZL2 Antibody

Human, Mouse, Rat

ELISA, WB

$370
Cat # A11230-1
100 μl/vial

MPZL2 Overview

Facts about Myelin protein zero-like protein 2.

MPZL2 3D structure. Source: alphafold

Myelin protein zero-like protein 2 (MPZL2)

Mediates homophilic cell-cell adhesion. .

Gene Information

Human
Gene Name:	MPZL2
Uniprot:	O60487
Entrez:	10205

Family

Belongs to:

myelin P0 protein family

Alternative Names

EVA1; EVAEpithelial V-like antigen 1EVA1myelin protein zero-like protein 2; MPZL2; myelin protein zero-like 2

Molecular Weight

Mass (kDA):
24.484 kDA

Genomic Context


Human

Location:	11q23.3
Sequence:	11; NC_000011.10 (118253416..118264536, complement)

Tissue Specificity

Expressed in thymocytes and thymic stromal cells; expression elevated in some T-cell leukemias.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Tissue Adhesions
Sclerosis
Male Infertility
Spinal Cord Injuries
Myelitis
Multiple Sclerosis
Idiopathic Hypereosinophilic Syndrome
Hair Diseases
Infertility
Multiple Trauma

Hypertrophy
Nervousness
Myelitis, Transverse
Dermatologic Disorders

Interacting Proteins

MPZL3

Pathways

Cell Adhesion
Spermatogenesis
Cell Maturation
Germ Cell Development
Cell Development
Thymus Development
Pachytene
Oligodendrocyte Development

Meiosis
Myelination
Oligodendrocyte Differentiation

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MPZL2

References

PMID: 9585423 by Guttinger M., et al. Epithelial V-like antigen (EVA), a novel member of the immunoglobulin superfamily, expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesis.

PMID: 29961571 by Wesdorp M., et al. MPZL2, encoding the epithelial junctional protein myelin protein zero-like 2, is essential for hearing in man and mouse.