Melanoregulin Antibodies

AND MREG ELISA kits, Melanoregulin Proteins

Many biological assays use antibodies to detect Melanoregulin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Melanoregulin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Melanoregulin antibodies...

We validate the specificity of these antibodies to Melanoregulin by testing them on tissues known to express MREG positively and negatively. Browse below to find the MREG antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MREG Infographic by Boster Bio

All MREG Products

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Applications

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DSU (MREG) (NM_018000) Human Recombinant Protein

Coomassie blue staining of purified MREG protein

$1249
Cat # PROTQ8N565
20 µg

DSU (MREG) (NM_018000) Human Over-expression Lysate

Human

$628
Cat # LS055686
20 µg, 100 µg

MREG Overview

Facts about Melanoregulin.

MREG 3D structure. Source: alphafold

Melanoregulin (MREG)

Plays a role in the incorporation of pigments into hair. May function in membrane fusion and modulate the biogenesis of disc membranes of photoreceptor rod cells (By similarity).

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Gene Information

Human
Gene Name:	MREG
Uniprot:	Q8N565
Entrez:	55686

Family

Belongs to:

melanoregulin family

Alternative Names

Dilute suppressor protein homolog; DSUFLJ10116; FLJ10116; melanoregulin; MGC90296; WDT2; whn-dependent transcript 2

Molecular Weight

Mass (kDA):
24.927 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (215939097..216034096, complement)

Tissue Specificity

Expressed in photoreceptor cells (at protein level).

Subcellular Localizations

Apical cell membrane; Peripheral membrane protein. Melanosome membrane; Lipid-anchor. Lysosome membrane; Lipid-anchor. Cytoplasmic vesicle membrane. Localizes to the inner segment and basal outer segment of rods in the retina.

Diseases

Malignant Neoplasm Of Prostate
Abdominal Pain
Stenosis
Small Intestinal Stenosis
Hermanski-pudlak Syndrome
Fibrosis
Malignant Neoplasms
Prostatic Neoplasms
Neoplasms
Pathologic Fistula

Albinism, Ocular
Pain
Crohn Disease
Albinism

Pathways

Pigmentation
Transport
Melanosome Transport
Membrane Fusion

PTMs

Lipoprotein

Palmitate

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MREG

References

PMID: 17260955 by Boesze-Battaglia K., et al. The tetraspanin protein peripherin-2 forms a complex with melanoregulin, a putative membrane fusion regulator.

PMID: 19240024 by Damek-Poprawa M., et al. Melanoregulin (MREG) modulates lysosome function in pigment epithelial cells.