Mrgpra3 Antibodies

AND Mrgpra3 ELISA kits, Mrgpra3 Proteins

Many biological assays use antibodies to detect Mrgpra3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mrgpra3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mrgpra3 antibodies...

We validate the specificity of these antibodies to Mrgpra3 by testing them on tissues known to express Mrgpra3 positively and negatively. Browse below to find the Mrgpra3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Mrgpra3 Infographic by Boster Bio

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Mrgpra3 Overview

Facts about Mas-related G-protein coupled receptor member A3.

Mrgpra3 3D structure. Source: alphafold

Mas-related G-protein coupled receptor member A3 (Mrgpra3)

Orphan receptor. May be a receptor for RFamide-family neuropeptides like NPFF and NPAF, which are analgesic in vivo.

May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity). Activated by the antimalarial drug chloroquine.

Gene Information

Mouse
Gene Name:	Mrgpra3
Uniprot:	Q91WW3
Entrez:	233222

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

Mas-related G-protein coupled receptor member A3

Molecular Weight

Mass (kDA):
34.483 kDA

Genomic Context


Mouse

Location:	7\|7 B3
Sequence:	7;

Tissue Specificity

Expressed exclusively in dorsal root ganglia and nodose ganglia. Expressed in a subset of sensory neurons that includes nociceptors. Expressed in the subclass of non-peptidergic sensory neurons that are IB4(+) and VR1(-).

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Mrgpra3

References

PMID: 11551509 by Dong X., et al. A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.

PMID: 20004959 by Liu Q., et al. Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus.