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- Table of Contents
Facts about Mas-related G-protein coupled receptor member D.
Beta-alanine at micromolar doses especially evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin- stimulated cAMP production in cells expressing the receptor, indicating that the receptor couples with G-protein G(q) and G(I).
| Human | |
|---|---|
| Gene Name: | MRGPRD |
| Uniprot: | Q8TDS7 |
| Entrez: | 116512 |

| Belongs to: |
|---|
| G-protein coupled receptor 1 family |

beta-Alanine Receptor; G-protein coupled receptor TGR7; mas-related G protein-coupled MRGD; MAS-related GPR, member D; mas-related G-protein coupled receptor member D; MRGD; MRGDTGR7; MRGPRD; TGR7
Mass (kDA):
36.118 kDA

| Human | |
|---|---|
| Location: | 11q13.3 |
| Sequence: | 11; NC_000011.10 (68980021..68980986, complement) |
Cell membrane; Multi-pass membrane protein. Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.





PMID: 12909716 by Zylka M.J., et al. Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.
PMID: 15037633 by Shinohara T., et al. Identification of a G protein-coupled receptor specifically responsive to beta-alanine.