Homeobox protein MSX-2 Antibodies

AND MSX2 ELISA kits, Homeobox protein MSX-2 Proteins

Many biological assays use antibodies to detect Homeobox protein MSX-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein MSX-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein MSX-2 antibodies...

We validate the specificity of these antibodies to Homeobox protein MSX-2 by testing them on tissues known to express MSX2 positively and negatively. Browse below to find the MSX2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Homeobox protein MSX-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MSX2 Western Blot Guide

MSX2 Infographic by Boster Bio

All MSX2 Products

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Specificity

Applications

Price

Anti-Hox8/MSX2 Antibody Picoband®

Western blot analysis of Hox8/MSX2 using anti-Hox8/MSX2 antibody (A01783-2)

Flow Cytometry analysis of PC-3 cells using anti-Hox8/MSX2 antibody (A01783-2)

Flow Cytometry analysis of RT4 cells using anti-Hox8/MSX2 antibody (A01783-2)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A01783-2
100 μg/vial

MSX2 (NM_002449) Human Over-expression Lysate

Human

$628
Cat # LS004488
20 µg, 100 µg

MSX2 Overview

Facts about Homeobox protein MSX-2.

MSX2 3D structure. Source: alphafold

Homeobox protein MSX-2 (MSX2)

Acts as a transcriptional regulator in bone growth. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation.

Probable morphogenetic role. May play a role in limb-pattern formation.

Gene Information

Human
Gene Name:	MSX2
Uniprot:	P35548
Entrez:	4488

Family

Belongs to:

Msh homeobox family

Alternative Names

CRS2; CRS2parietal foramina 1; FPP; Homeobox protein Hox-8; homeobox protein MSX-2; Hox8; HOX8msh homeobox homolog 2 (Drosophila); msh (Drosophila) homeo box homolog 2; msh homeo box 2; msh homeobox 2; msh homeobox homolog 2; MSH; MSX2; PFM; PFM1

Molecular Weight

Mass (kDA):
28.897 kDA

Genomic Context


Human

Location:	5q35.2
Sequence:	5; NC_000005.10 (174724582..174730896)

Subcellular Localizations

Nucleus.

Diseases

Craniosynostosis
Malignant Neoplasms
Crest Syndrome
Neoplasms
Vascular Calcification
Calcinosis
Congenital Abnormality
Carcinoma
Cleft Palate
Craniofacial Abnormalities
Diabetes Mellitus
Cell Transformation, Neoplastic

Dysplasia
Hyperplasia
Atherosclerosis
Limb Deformities, Congenital
Malignant Neoplasm Of Breast
Mammary Neoplasms
Malignant Paraganglionic Neoplasm

Pathways

Osteoblast Differentiation
Ossification
Cell Proliferation
Cell Death
Limb Development
Programmed Cell Death
Cell Differentiation
Regeneration
Bone Development
Localization
Pathogenesis
Cell Migration
Amelogenesis

Methylation
Bmp Signaling Pathway
Gland Development
Gastrulation
Odontogenesis
Cell Growth
Angiogenesis

PTMs

Phosphorylation
Methylation
Sumoylation
Biotinylation
Demethylation

Cleavage
Gamma-carboxylation
Acetylation
Oxidation
Ubiquitination

Research Areas

Apoptosis
Inhibitors, Activators and Regulators

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MSX2

References

PMID: 8101453 by Hodgkinson J.E., et al. Expression of a human homeobox-containing gene is regulated by 1,25(OH)2D3 in bone cells.

PMID: 8106171 by Jabs E.W., et al. A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis.