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MT-ND1 Antibodies
AND MT-ND1 ELISA kits, MT-ND1 Proteins
Many biological assays use antibodies to detect MT-ND1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MT-ND1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MT-ND1 antibodies...
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MT-ND1 Infographic by Boster Bio
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MT-ND1 Overview
Facts about NADH-ubiquinone oxidoreductase chain 1.
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1)
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.
The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | MT-ND1 |
| Uniprot: | P03886 |
| Entrez: | |
Family
| Belongs to: |
|---|
| complex I subunit 1 family |
Alternative Names
NADH-ubiquinone oxidoreductase chain 1
Molecular Weight
Mass (kDA):
35.661 kDA
Genomic Context
| Human | |
|---|---|
| Location: | |
| Sequence: | ; |
Subcellular Localizations
Mitochondrion inner membrane; Multi-pass membrane protein.
Diseases
- Leber hereditary optic neuropathy (LHON)
Interacting Proteins
- NAMPT
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MT-ND1
bosterbio.com/bosterbio-gene-info-cards/MT-ND1
References
PMID: 7219534 by Anderson S., et al. Sequence and organization of the human mitochondrial genome.
PMID: 7530363 by Horai S., et al. Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs.