MT-RNR1 Antibodies

AND MT-RNR1 ELISA kits, MT-RNR1 Proteins

Many biological assays use antibodies to detect MT-RNR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MT-RNR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MT-RNR1 antibodies...

We validate the specificity of these antibodies to MT-RNR1 by testing them on tissues known to express MT-RNR1 positively and negatively. Browse below to find the MT-RNR1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MT-RNR1 Infographic by Boster Bio

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MT-RNR1 Overview

Facts about Mitochondrial-derived peptide MOTS-c.

MT-RNR1 3D structure. Source: alphafold

Mitochondrial-derived peptide MOTS-c (MT-RNR1)

Regulates insulin sensitivity and metabolic homeostasis. Inhibits the folate cycle, thus reducing de novo purine biosynthesis which leads to the accumulation of the de novo purine synthesis intermediate 5-aminoimidazole-4-carboxamide (AICAR) and the activation of the metabolic regulator 5'-AMP-activated protein kinase (AMPK).

Protects against age-dependent and diet-induced insulin resistance in addition to diet-induced obesity. .

Gene Information

Human
Gene Name:	MT-RNR1
Uniprot:	A0A0C5B5G6
Entrez:

Family

Belongs to:

No superfamily

Alternative Names

Mitochondrial-derived peptide MOTS-c

Molecular Weight

Mass (kDA):
2.175 kDA

Genomic Context


Human

Location:
Sequence:	;

Tissue Specificity

Detected in plasma (at protein level).

Subcellular Localizations

Secreted.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MT-RNR1

References

PMID: 25738459 by Lee C., et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.

PMID: 26289118 by Fuku N., et al. The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?