MTMR14 Antibodies

AND MTMR14 ELISA kits, MTMR14 Proteins

Many biological assays use antibodies to detect MTMR14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTMR14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTMR14 antibodies...

We validate the specificity of these antibodies to MTMR14 by testing them on tissues known to express MTMR14 positively and negatively. Browse below to find the MTMR14 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MTMR14 Infographic by Boster Bio

All MTMR14 Products

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Specificity

Applications

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Anti-MTMR14 Antibody

Western blot analysis of extracts of MCF7 cells, using MTMR14 antibody at 1:1000 dilution

Immunofluorescence analysis of NIH/3T3 cells using MTMR14 Rabbit pAb at dilution of 1:100

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A08168
100ul

MTMR14 (NM_022485) Human Recombinant Protein

$1062
Cat # PROTQ8NCE2
20 µg

Anti-MTMR14 Mouse Monoclonal Antibody [Clone ID: OTI6B6]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MTMR14 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (10ug) from 10 Human tissue by using anti-MTMR14 monoclonal antibody at 1:200 (1: Testis; 2: Omentum; 3: Uterus; 4: Breast; 5: Brain; 6: Liver; 7: Ovary; 8: Thyroid gland; 9: colon;10: spleen)

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-MTMR14 monoclonal antibody

Dog, Human, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M08168
100 µl

MTMR14 (NM_001077526) Human Over-expression Lysate

MTMR14 Human Over-expression Lysates NM_001077525

Human

$628
Cat # LS064419
20 µg, 100 µg

MTMR14 Overview

Facts about Myotubularin-related protein 14.

MTMR14 3D structure. Source: alphafold

Myotubularin-related protein 14 (MTMR14)

Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P3. .

Gene Information

Human
Gene Name:	MTMR14
Uniprot:	Q8NCE2
Entrez:	64419

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

C3orf29FLJ11546; chromosome 3 open reading frame 29; EC 3.1.3.-; egg-derived tyrosine phosphatase homolog; FLJ22405; FLJ46453; FLJ90311; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; hEDTP; hJumpy; jumpy; myotubularin related protein 14; myotubularin-related protein 14; NS5ATP4ABP1

Molecular Weight

Mass (kDA):
72.203 kDA

Genomic Context


Human

Location:	3p25.3
Sequence:	3; NC_000003.12 (9649465..9702393)

Tissue Specificity

Expressed in various tissues, including heart, skeletal muscle, placenta, liver, lung, kidney and pancreas.

Subcellular Localizations

Cytoplasm. Found in reticular structures and plasma membrane ruffles. Concentrated near the nucleus.

Diseases

Myopathy
Congenital Structural Myopathy
Congenital Myopathy (disorder)
Weakness
Neuromuscular Diseases
De Novo Mutation
Congenital Heart Defects
Malignant Neoplasms
Congenital Myotonic Dystrophy
Neonatal Hypotonia
Myotonic Dystrophy
External Ophthalmoplegia

Ophthalmoplegia
Asphyxia
Polyhydramnios
Genetic Diseases, X-linked
Muscle Hypotonia
Dystrophy

Pathways

Autophagy
Aging
Regulation Of Autophagy
Endocytosis
Localization

PTMs

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTMR14

References

PMID: 17008356 by Tosch V., et al. A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy.