MTMR4 Antibodies

AND MTMR4 ELISA kits, MTMR4 Proteins

Many biological assays use antibodies to detect MTMR4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTMR4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTMR4 antibodies...

We validate the specificity of these antibodies to MTMR4 by testing them on tissues known to express MTMR4 positively and negatively. Browse below to find the MTMR4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MTMR4 Infographic by Boster Bio

All MTMR4 Products

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Anti-Myotubularin-related protein 4 MTMR4 Antibody

Western blot analysis of extracts of various cell lines, using MTMR4 antibody at 1:1000 dilution

Immunofluorescence analysis of L929 cells using MTMR4 Polyclonal Antibody at dilution of 1:100

Immunofluorescence analysis of U-2 OS cells using MTMR4 Polyclonal Antibody at dilution of 1:100

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A09354
100ul

MTMR4 Overview

Facts about Myotubularin-related protein 4.

MTMR4 3D structure. Source: alphafold

Myotubularin-related protein 4 (MTMR4)

Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3).

Gene Information

Human
Gene Name:	MTMR4
Uniprot:	Q9NYA4
Entrez:	9110

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

EC 3.1.3.48; FYVE-DSP2; KIAA0647zinc finger, FYVE domain containing 11; myotubularin related protein 4; ZFYVE11FYVE domain-containing dual specificity protein phosphatase 2; Zinc finger FYVE domain-containing protein 11

Molecular Weight

Mass (kDA):
133.353 kDA

Genomic Context


Human

Location:	17q22
Sequence:	17; NC_000017.11 (58489537..58518109, complement)

Tissue Specificity

Expressed in brain, heart, kidney, spleen, liver, colon, testis, muscle, placenta, thyroid gland, pancreas, ovary, prostate, skin, peripheral blood, and bone marrow.

Subcellular Localizations

Cytoplasm. Membrane; Peripheral membrane protein. Localized to perinuclear region.

Diseases

Thyroid Neoplasm
Cardiovascular Diseases
Muscle Twitch
Malignant Neoplasms
Neoplasms
Muscular Atrophy
Papillary Thyroid Carcinoma
Thyroid Diseases

Atrophy
Carcinoma, Papillary
Malignant Neoplasm Of Thyroid

Interacting Proteins

SMAD2
SMAD3

Pathways

Transport
Aging
Proteolysis
Immune Response
Ovulation
Muscle Atrophy
Localization

Skeletal Muscle Atrophy

PTMs

Dephosphorylation

Phosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTMR4

References

PMID: 11302699 by Zhao R., et al. FYVE-DSP2, a FYVE domain-containing dual specificity protein phosphatase that dephosphorylates phosphatidylinositol 3-phosphate.