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- Table of Contents
Facts about Mucin-17.
| Human | |
|---|---|
| Gene Name: | MUC17 |
| Uniprot: | Q685J3 |
| Entrez: | 140453 |

| Belongs to: |
|---|
| No superfamily |

membrane mucin MUC17; MUC-3; mucin 17, cell surface associated; secreted mucin MUC17; small intestinal mucin MUC3; small intestinal mucin-3
Mass (kDA):
451.741 kDA

| Human | |
|---|---|
| Location: | 7q22.1 |
| Sequence: | 7; NC_000007.14 (101020081..101058859) |
Expressed almost exclusively in the intestine. Expression is especially high in both the duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression is detected in goblet cells. Highly expressed in pancreatic adenocarcinoma tissue (at protein level). Expression is not detectable in normal pancreas, in pancreatitis or in cell lines derived from other cancers.
[Isoform 1]: Cell membrane; Single-pass membrane protein.; [Isoform 2]: Secreted. Cell membrane.




PMID: 16737958 by Moniaux N., et al. Characterization of human mucin MUC17. Complete coding sequence and organization.
PMID: 9299468 by Van Klinken B.J.-W., et al. Molecular cloning of human MUC3 cDNA reveals a novel 59 amino acid tandem repeat region.