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- Table of Contents
Mevalonate kinase Antibodies
AND MVK ELISA kits, Mevalonate kinase Proteins
Many biological assays use antibodies to detect Mevalonate kinase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mevalonate kinase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mevalonate kinase antibodies...
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MVK Infographic by Boster Bio
All MVK Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$480
Cat # EKC1772
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1772
1 kit, containing one 96-well plate and all necessary reagents
Human
ELISA, Flow Cytometry, IP, IF, IHC, WB
$370
Cat # A02465-2
100 μg/vial
Cat # A02465-2
100 μg/vial
MVK Overview
Facts about Mevalonate kinase.
Mevalonate kinase (MVK)
Catalyzes the phosphorylation of mevalonate into mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis (PubMed:9325256, PubMed:18302342). .
Gene Information
| Human | |
|---|---|
| Gene Name: | MVK |
| Uniprot: | Q03426 |
| Entrez: | 4598 |
Family
| Belongs to: |
|---|
| GHMP kinase family |
Alternative Names
EC 2.7.1.36; LH receptor mRNA-binding protein; LRBP; mevalonate kinase (mevalonic aciduria); mevalonate kinase 1; mevalonate kinase; Mevalonic Aciduria; MKFLJ96772; MVK; MVLK; POROK3
Molecular Weight
Mass (kDA):
42.451 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q24.11 |
| Sequence: | 12; NC_000012.12 (109573461..109598125) |
Subcellular Localizations
Cytoplasm. Peroxisome.
Diseases
- Familial Mediterranean Fever
- Deficiency Of Mevalonate Kinase
- Hyper Igd Syndrome
- Hypergammaglobulinemia
- Relapsing Fever
- Brucellosis
- Mevalonic Aciduria
- Inflammation
- Carcinogenesis
- Malignant Neoplasms
- Neoplasms
Interacting Proteins
- POT1
Pathways
- Pathogenesis
- Cell Proliferation
- Immune Response
- Translation
- Regeneration
- Cell Death
- Excretion
- Secretion
- Transport
- Innate Immune Response
- Cell Killing
- Luteinization
- Cholesterol Homeostasis
PTMs
- Oxidation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MVK
bosterbio.com/bosterbio-gene-info-cards/MVK
References
PMID: 1377680 by Schafer B.L., et al. Molecular cloning of human mevalonate kinase and identification of a missense mutation in the genetic disease mevalonic aciduria.
PMID: 8302606 by Graef E., et al. Insertional activation of mevalonate kinase by hepatitis B virus DNA in a human hepatoma cell line.