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- Table of Contents
Facts about Matrix remodeling-associated protein 8.
.
| Human | |
|---|---|
| Gene Name: | MXRA8 |
| Uniprot: | Q9BRK3 |
| Entrez: | 54587 |

| Belongs to: |
|---|
| No superfamily |

Asp3; DICAM; Limitrin; Matrix-Remodeling-Associated Protein 8; MXRA8
Mass (kDA):
49.132 kDA

| Human | |
|---|---|
| Location: | 1p36.33 |
| Sequence: | 1; NC_000001.11 (1352689..1363541, complement) |
Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Cytoplasm. Cell projection, cilium membrane. Nucleus. Primarily localizes to the cell membrane (PubMed:23386276). Detected in the cilium of primary chondrocytes (By similarity). Highly expressed at areas of cell-cell contact and may localize to tight junctions (By similarity). Also found in the nucleus where it is detected in the soluble (as opposed to chromatin-bound) fraction (PubMed:23386276).




PMID: 14603461 by Yonezawa T., et al. Limitrin, a novel immunoglobulin superfamily protein localized to glia limitans formed by astrocyte endfeet.
PMID: 22492581 by Jung Y.K., et al. DICAM inhibits osteoclast differentiation through attenuation of the integrin alphaVbeta3 pathway.