c-Myc-binding protein Antibodies

AND MYCBP ELISA kits, c-Myc-binding protein Proteins

Many biological assays use antibodies to detect c-Myc-binding protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with c-Myc-binding protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop c-Myc-binding protein antibodies...

We validate the specificity of these antibodies to c-Myc-binding protein by testing them on tissues known to express MYCBP positively and negatively. Browse below to find the MYCBP antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for c-Myc-binding protein? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the MYCBP IHC Guide

MYCBP Infographic by Boster Bio

All MYCBP Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MYCBP Antibody Picoband®

IHC analysis of MYCBP using anti-MYCBP antibody (A06216-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A06216-2
100 µg/vial

MYCBP (NM_012333) Human Over-expression Lysate

Human

$628
Cat # LS026292
20 µg, 100 µg

MYCBPAP (NM_032133) Human Over-expression Lysate

Human

$960
Cat # LS084073
20 µg, 100 µg

MYCBP (NM_012333) Human Recombinant Protein

Coomassie blue staining of purified MYCBP protein

$1249
Cat # PROTQ99417
20 µg

MYCBP Overview

Facts about c-Myc-binding protein.

MYCBP 3D structure. Source: alphafold

c-Myc-binding protein (MYCBP)

May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.

Gene Information

Human
Gene Name:	MYCBP
Uniprot:	Q99417
Entrez:	26292

Family

Belongs to:

AMY1 family

Alternative Names

AMY-1AMY1; Associate of Myc 1; associate of myc-1; c-myc binding protein; C-Myc-binding protein; FLJ41056

Molecular Weight

Mass (kDA):
11.967 kDA

Genomic Context


Human

Location:	1p34.3
Sequence:	1; NC_000001.11 (38862490..38873378, complement)

Tissue Specificity

Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung.

Subcellular Localizations

Cytoplasm. Nucleus. Mitochondrion. Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Neoplasm Metastasis
Cell Transformation, Neoplastic
Mammary Neoplasms
Hyperplasia
Metastatic Malignant Neoplasm To The Lymph Node
Lymphoma
Malignant Neoplasm Of Prostate
Malignant Neoplasm Of Stomach
Stomach Neoplasms
Leukemia

Medulloblastoma
Cerebellar Neoplasms
Prostatic Neoplasms
Colorectal Cancer
Cell Invasion
Tissue Adhesions
Malignant Neoplasm Of Breast

Interacting Proteins

ARFGEF1
ARFGEF2
MYCBPAP

Pathways

Cell Cycle
Cell Proliferation
Cell Growth
Cell Adhesion
Spermatogenesis
Cell Differentiation
Oncogenesis
Localization
Cell Migration
Cell Cycle Arrest
Interphase
Glycolysis

Tricarboxylic Acid Cycle
Erythrocyte Differentiation
Reverse Transcription
Translation
Cell Motility
Wound Healing
Enucleation

PTMs

Phosphorylation
Cleavage
Methylation

Reduction
Acetylation
Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYCBP

References

PMID: 9797456 by Taira T., et al. AMY-1, a novel C-MYC binding protein that stimulates transcription activity of C-MYC.

PMID: 11483602 by Furusawa M., et al. AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP- dependent protein kinase.