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- Table of Contents
Myosin-10 Antibodies
AND MYH10 ELISA kits, Myosin-10 Proteins
Many biological assays use antibodies to detect Myosin-10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myosin-10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myosin-10 antibodies...
Designing a Western blot for Myosin-10? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MYH10 Western Blot GuideMYH10 Infographic by Boster Bio
All MYH10 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02681-1
100 μg/vial
Cat # A02681-1
100 μg/vial
MYH10 Overview
Facts about Myosin-10.
Myosin-10 (MYH10)
Cellular myosin that seems to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (from the central part but not the margins of spreading cells), and lamellipodial extension; this purpose is mechanically antagonized by MYH9. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MYH10 |
| Uniprot: | P35580 |
| Entrez: | 4628 |
Family
| Belongs to: |
|---|
| TRAFAC class myosin-kinesin ATPase superfamily |
Alternative Names
cellular myosin heavy chain, type B type B; Cellular myosin heavy chain, type B; heavy polypeptide 10, non-muscle; MGC134913; MGC134914; Myosin heavy chain 10; Myosin heavy chain, non-muscle IIb; myosin heavy chain, nonmuscle type B; myosin, heavy chain 10, non-muscle; myosin-10; near to the ATP binding region; NMMHC II-b; NMMHCB; NMMHC-B; NMMHC-IIB; Non-muscle myosin heavy chain B; nonmuscle myosin heavy chain IIB; Non-muscle myosin heavy chain IIb; nonmuscle myosin heavy chain-B; nonmuscle myosin II heavy chain-B
Molecular Weight
Mass (kDA):
228.999 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.1 |
| Sequence: | 17; NC_000017.11 (8474205..8631369, complement) |
Tissue Specificity
Isoform 1 is expressed in cerebellum and spinal chord. Isoform 2 is expressed in cerebrum and retina. Isoform 3 is expressed in the cerebrum and to a much lower extent in cerebellum.
Subcellular Localizations
Cell projection, lamellipodium. Colocalizes with MCC at the leading edge of migrating cells.
Diseases
- Tissue Adhesions
- Blood Platelet Disorders
- Leukemia, Myelocytic, Acute
- Myeloid Leukemia
- Leukemia
- Juvenile Neuronal Ceroid Lipfuscinosis
- Myelomonocytic Leukemia
- Jacobsen Distal 11q Deletion Syndrome
- Hydrocephalus
- Infertility
- Segmental Glomerulosclerosis
- Cardiovascular Diseases
- Malignant Neoplasms
Pathways
- Cytokinesis
- Cell Adhesion
- Cell Migration
- Gene Silencing
- Meiosis Ii
- Mitosis
- Neurogenesis
- Megakaryocyte Differentiation
- Localization
- Cell Division
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYH10
bosterbio.com/bosterbio-gene-info-cards/MYH10
References
PMID: 7499478 by Phillips C.L., et al. Cloning of the cDNA encoding human nonmuscle myosin heavy chain-B and analysis of human tissues with isoform-specific antibodies.
PMID: 8690889 by Abdelhaleem M.M., et al. Leukophysin: an RNA helicase A-related molecule identified in cytotoxic T cell granules and vesicles.
1 Publications of Boster Myosin-10 Antibodies & ELISA Kits
- PubMed ID: 10.3390/ijms221810034, Extracellular Calcium Ion Concentration Regulates Chondrocyte Elastic Modulus an...
*More publications can be found for each product on its corresponding product page