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- Table of Contents
Designing an IHC experiment for Myosin-11? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MYH11 IHC GuideFacts about Myosin-11.
| Human | |
|---|---|
| Gene Name: | MYH11 |
| Uniprot: | P35749 |
| Entrez: | 4629 |

| Belongs to: |
|---|
| TRAFAC class myosin-kinesin ATPase superfamily |

AAT4; FAA4; MYH11 myosin, heavy chain 11, smooth muscle; MYH11; SMHC; SMMHC; Smooth muscle myosin heavy chain
Mass (kDA):
227.339 kDA

| Human | |
|---|---|
| Location: | 16p13.11 |
| Sequence: | 16; NC_000016.10 (15703135..15857032, complement) |
Smooth muscle; expressed in the umbilical artery, bladder, esophagus and trachea. Isoform 1 is mostly found in slowly contracting tonic muscles.
Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Thick filaments of the myofibrils.






PMID: 16000639 by Leguillette R., et al. (+)Insert smooth muscle myosin heavy chain (SM-B) isoform expression in human tissues.
PMID: 7684189 by Matsuoka R., et al. Human smooth muscle myosin heavy chain gene mapped to chromosomal region 16q12.