E3 ubiquitin-protein ligase MARCHF11 (Marchf11)

E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases take ubiquitin from an E2 ubiquitin-conjugating enzyme in the shape of a thioester and then directly transfer the ubiquitin to targeted substrates.

May play a role in ubuquitin-dependent protein sorting in developmenting spermatids. .