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- Table of Contents
Facts about Meiosis-specific coiled-coil domain-containing protein MEIOC.
The purpose may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an protracted meiotic prophase I by correctly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle (PubMed:28380054).
| Mouse | |
|---|---|
| Gene Name: | Meioc |
| Uniprot: | A2AG06 |
| Entrez: | 268491 |

| Belongs to: |
|---|
| No superfamily |

Meiosis-specific coiled-coil domain-containing protein MEIOC
Mass (kDA):
108.83 kDA

| Mouse | |
|---|---|
| Location: | 11|11 E1 |
| Sequence: | 11; |
Expressed specifically in fetal ovary and postnatal and adult testes (at protein level) (PubMed:26742488). In adult testis expressed in spermatocytes, beginning in preleptotene and extending through most stages of meiotic prophase I, including leptotene, zygotene, and pachytene (PubMed:28380054).

PMID: 26742488 by Abby E., et al. Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts.
PMID: 28380054 by Soh Y.Q.S., et al. Meioc maintains an extended meiotic prophase I in mice.