Homeobox protein MOX-2 Antibodies

AND MEOX2 ELISA kits, Homeobox protein MOX-2 Proteins

Many biological assays use antibodies to detect Homeobox protein MOX-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein MOX-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein MOX-2 antibodies...

We validate the specificity of these antibodies to Homeobox protein MOX-2 by testing them on tissues known to express MEOX2 positively and negatively. Browse below to find the MEOX2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Homeobox protein MOX-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MEOX2 Western Blot Guide

MEOX2 Infographic by Boster Bio

All MEOX2 Products

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Product

Figures

Specificity

Applications

Price

Anti-MEOX2 Antibody Picoband®

Western blot analysis of MEOX2 using anti-MEOX2 antibody (A05167-2)

Flow Cytometry analysis of A549 cells using anti-MEOX2 antibody (A05167-2)

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # A05167-2
100 μg/vial

MEOX2 Colorimetric Cell-Based ELISA

Western blot analysis of extracts from COLO205 cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1733
1 kit, containing one 96-well plate and all necessary reagents

MEOX 2 (MEOX2) (NM_005924) Human Over-expression Lysate

Human

$628
Cat # LS004223
20 µg, 100 µg

Human MEOX2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP50222
Starting from 10ug

MEOX2 Overview

Facts about Homeobox protein MOX-2.

MEOX2 3D structure. Source: alphafold

Homeobox protein MOX-2 (MEOX2)

Mesodermal transcription factor that plays an integral role in somitogenesis and is needed for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation.

While it activates CDKN1A at a DNA-dependent fashion, it disturbs CDKN2A in a DNA-independent way (PubMed:22206000). May have a regulatory function when quiescent vascular smooth muscle cells reenter the cell cycle.

Gene Information

Human
Gene Name:	MEOX2
Uniprot:	P50222
Entrez:	4223

Family

Belongs to:

No superfamily

Alternative Names

growth arrest-specific homeo box; Growth arrest-specific homeobox; homeobox protein MOX-2; mesenchyme homeo box 2 (growth arrest-specific homeo box); mesenchyme homeobox 2GAX; MOX2mesenchyme homeobox 2 (growth arrest-specific homeo box)

Molecular Weight

Mass (kDA):
33.594 kDA

Genomic Context


Human

Location:	7p21.2
Sequence:	7; NC_000007.14 (15611212..15686683, complement)

Tissue Specificity

Embryo and placenta.

Subcellular Localizations

Nucleus. Nucleus speckle.

Diseases

Neoplasms
Tumor Angiogenesis
Malignant Neoplasms
Alzheimer's Disease
Atherosclerosis
Cardiovascular Diseases
Vascular System Injuries
Hypertensive Disease
Hypoxia
Growth Arrest
Cell Transformation, Neoplastic
Lung Neoplasms
Arteriosclerosis

Hyperplasia
Kidney Neoplasm
Congenital Abnormality
Cleft Palate
Nephroblastoma
Truncus Arteriosus, Persistent
Carotid Artery Injuries

Pathways

Cell Proliferation
Angiogenesis
Cell Cycle
Somitogenesis
Pathogenesis
Tube Formation
Cell Cycle Arrest
Gastrulation
Localization
Cell Growth
Cell Activation
Cell Migration
Mesoderm Formation

Endothelial Cell Activation
Transport
Palate Development
Senescence
Cell Death
Cell Adhesion
Lung Development

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MEOX2

References

PMID: 7607679 by Grigoriou M., et al. Isolation of the human MOX2 homeobox gene and localization to chromosome 7p22.1-p21.3.

PMID: 7713505 by Lepage D.F., et al. Molecular cloning and localization of the human GAX gene to 7p21.