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- Table of Contents
Facts about Mas-related G-protein coupled receptor member A1.
Its effect is mediated by G(q) and G(11) proteins. May regulate the use of nociceptive neurons by modulation of pain perception.
| Mouse | |
|---|---|
| Gene Name: | Mrgpra1 |
| Uniprot: | Q91WW5 |
| Entrez: | 233221 |

| Belongs to: |
|---|
| G-protein coupled receptor 1 family |

Mas-related G-protein coupled receptor member A1
Mass (kDA):
34.381 kDA

| Mouse | |
|---|---|
| Location: | 7|7 B3 |
| Sequence: | 7; |
Expressed in a subset of sensory neurons that includes nociceptors. Expressed in the subclass of non-peptidergic sensory neurons that are IB4(+) and VR1(-).

PMID: 11551509 by Dong X., et al. A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.
PMID: 12397184 by Han S.-K., et al. Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway.