Mas-related G-protein coupled receptor member A1 (Mrgpra1)

Orphan receptor activated by a subset of RFamide-family neuropeptides like FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Its effect is mediated by G(q) and G(11) proteins. May regulate the use of nociceptive neurons by modulation of pain perception.