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- Table of Contents
Facts about Transcription termination factor 1a, mitochondrial.
Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping.
| Mouse | |
|---|---|
| Gene Name: | Mterf1a |
| Uniprot: | Q8CHZ9 |
| Entrez: | 545725 |

| Belongs to: |
|---|
| mTERF family |

Transcription termination factor 1a, mitochondrial
Mass (kDA):
43.815 kDA

| Mouse | |
|---|---|
| Location: | 5|5 A1 |
| Sequence: | 5; |
Predominantly expressed in heart and liver, with extremely low levels in other tissues (PubMed:15582606). Expressed strongly in the heart and at lower levels in brain, liver and kidney (PubMed:23562081).

PMID: 15582606 by Li X., et al. Cloning and characterization of mouse mTERF encoding a mitochondrial transcriptional termination factor.
PMID: 23562081 by Terzioglu M., et al. MTERF1 binds mtDNA to prevent transcriptional interference at the light-strand promoter but is dispensable for rRNA gene transcription regulation.