Nanos homolog 2 Antibodies

AND NANOS2 ELISA kits, Nanos homolog 2 Proteins

Many biological assays use antibodies to detect Nanos homolog 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nanos homolog 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nanos homolog 2 antibodies...

We validate the specificity of these antibodies to Nanos homolog 2 by testing them on tissues known to express NANOS2 positively and negatively. Browse below to find the NANOS2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NANOS2 Infographic by Boster Bio

All NANOS2 Products

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NANOS2 (NM_001029861) Human Recombinant Protein

Coomassie blue staining of purified NANOS2 protein

$1249
Cat # PROTP60321
20 µg

NANOS2 (NM_001029861) Human Over-expression Lysate

Human

$628
Cat # LS339345
20 µg, 100 µg

Anti-NANOS2 Antibody Picoband®

Western blot analysis of NANOS2 using anti-NANOS2 antibody (A07978-2)

IHC analysis of NANOS2 using anti-NANOS2 antibody (A07978-2)

Human

IHC, WB

$370
Cat # A07978-2
100 μg/vial

NANOS2 Overview

Facts about Nanos homolog 2.

NANOS2 3D structure. Source: alphafold

Nanos homolog 2 (NANOS2)

Plays a crucial role in the sexual differentiation of germ cells by encouraging the male destiny but suppressing the female destiny. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male destiny.

Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the upkeep of the spermatogonial stem cell population.

Gene Information

Human
Gene Name:	NANOS2
Uniprot:	P60321
Entrez:	339345

Family

Belongs to:

nanos family

Alternative Names

nanos homolog 2 (Drosophila); nanos homolog 2; Nanos2; NOS2NOS-2

Molecular Weight

Mass (kDA):
15.132 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (45913214..45914778, complement)

Tissue Specificity

Testis and ovary. Expression found in several spermatogenic stages: in cells on the periphery of the tubules which could correspond to spermatogonia, in spermatocytes and in round spermatids (at protein level).

Subcellular Localizations

Cytoplasm. Cytoplasm, P-body. Cytoplasm, perinuclear region. Localizes at P-bodies during gonocyte development (By similarity). More abundant in perinuclear region of the cytoplasm of the germ cells of the adult testis.