Nck-associated protein 1-like (NCKAP1L)

Essential hematopoietic-specific regulator of the actin cytoskeleton (Probable). Controls lymphocyte development, activation, proliferation and homeostasis, erythrocyte membrane stability, in addition to phagocytosis and migration by neutrophils and macrophages (PubMed:16417406, PubMed:17696648).

Part of the WAVE2 complex which signals downstream of RAC to excite F- actin polymerization. Required for stabilization and/or translation of the WAVE2 complex proteins in hematopoietic cells (By similarity).