NCKAP5L Antibodies

AND NCKAP5L ELISA kits, NCKAP5L Proteins

Many biological assays use antibodies to detect NCKAP5L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NCKAP5L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NCKAP5L antibodies...

We validate the specificity of these antibodies to NCKAP5L by testing them on tissues known to express NCKAP5L positively and negatively. Browse below to find the NCKAP5L antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NCKAP5L Infographic by Boster Bio

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NCKAP5L Overview

Facts about Nck-associated protein 5-like.

NCKAP5L 3D structure. Source: alphafold

Nck-associated protein 5-like (NCKAP5L)

Regulates microtubule organization and stabilization. Promotes microtubule growth and bundling formation and stabilizes microtubules by raising extreme acetylation of microtubules (PubMed:26482847, PubMed:26485573).

Both tubulin-binding and homodimer formation are required for NCKAP5L-mediated microtubule bundle formation (PubMed:26485573). .

Gene Information

Human
Gene Name:	NCKAP5L
Uniprot:	Q9HCH0
Entrez:	57701

Family

Belongs to:

No superfamily

Alternative Names

FLJ36581; KIAA1602; NCK-associated protein 5-like

Molecular Weight

Mass (kDA):
139.013 kDA

Genomic Context


Human

Location:	12q13.12
Sequence:	12; NC_000012.12 (49791139..49828750, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes to microtubule plus ends (PubMed:26485573, PubMed:26482847). Associates with centrosomes during interphase, but dissociates from these structures from the onset of mitosis (PubMed:26549230).

Diseases

Autistic Disorder

Pathways

Proteolysis

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NCKAP5L

References

PMID: 26549230 by Mori Y., et al. Phosphorylation of the centrosomal protein, Cep169, by Cdk1 promotes its dissociation from centrosomes in mitosis.

PMID: 26482847 by Mori Y., et al. Microtubule-bundling activity of the centrosomal protein, Cep169, and its binding to microtubules.