JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

Nicalin Antibodies

AND NCLN ELISA kits, Nicalin Proteins

Many biological assays use antibodies to detect Nicalin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nicalin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nicalin antibodies...

We validate the specificity of these antibodies to Nicalin by testing them on tissues known to express NCLN positively and negatively. Browse below to find the NCLN antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: GPR108

NCLN Infographic by Boster Bio

NCLN protein infographic

All NCLN Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-NCLN/Nicalin Antibody

1 Q&As

Immunohistochemical analysis of paraffin-embedded Human colon cancer

Immunohistochemical analysis of paraffin-embedded Human colon cancer

Western blot analysis of lysates from HepG2 and HUVEC cells, using NCLN Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$335
Cat # A12284
100ul

Anti-Nicalin NCLN Antibody

Western blot analysis of NCLN in mouse heart tissue lysate with NCLN antibody at 0

Western blot analysis of NCLN in mouse heart tissue lysate with NCLN antibody at 0

Immunohistochemistry of NCLN in human heart tissue with NCLN antibody at 2

Immunofluorescence of NCLN in human heart tissue with NCLN antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A12284-1
0.1 mg

NCLN (NM_020170) Human Over-expression Lysate

NCLN Human Over-expression Lysates NM_020170

NCLN Human Over-expression Lysates NM_020170

Human

$628
Cat # LS056926
20 µg, 100 µg

Anti-NCLN Antibody Picoband®

Western blot analysis of NCLN using anti-NCLN antibody (A12284-2)

Western blot analysis of NCLN using anti-NCLN antibody (A12284-2)

IHC analysis of NCLN using anti-NCLN antibody (A12284-2)

IF analysis of NCLN using anti-NCLN antibody (A12284-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A12284-2
100 μg/vial

NCLN Overview

Facts about Nicalin.

NCLN 3D structure

NCLN 3D structure. Source: alphafold

Nicalin (NCLN)

May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. .

.

Gene Information

Human
Gene Name:	NCLN
Uniprot:	Q969V3
Entrez:	56926

Gene Information

Family

Belongs to:

nicastrin family

Family

Alternative Names

Ncl-1; NCLN; NET59; nicalin homolog (zebrafish); nicalin homolog (zebrefish); Nicalin; Nicastrin-like protein

Molecular Weight

Mass (kDA):
62.974 kDA

Molecular Weight

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (3185930..3209575)

Tissue Specificity

Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass membrane protein.

Subcellular Localization

Diseases

Neoplasms
Neoplasms, Experimental
Alzheimer's Disease

Disease

Interacting Proteins

KRTAP5-9

Interacting Proteins

Pathways

Rna Interference

Pathways

PTMs

Cleavage

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NCLN

References

PMID: 15257293 by Haffner C., et al. Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

PMID: 20538592 by Dettmer U., et al. Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex.