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- Table of Contents
NCR2 Antibodies
AND NCR2 ELISA kits, NCR2 Proteins
Many biological assays use antibodies to detect NCR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NCR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NCR2 antibodies...
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NCR2 Infographic by Boster Bio
All NCR2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M05962-1
100 μl/vial
Cat # M05962-1
100 μl/vial
NCR2 Overview
Facts about Natural cytotoxicity triggering receptor 2.
Natural cytotoxicity triggering receptor 2 (NCR2)
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NCR2 |
| Uniprot: | O95944 |
| Entrez: | 9436 |
Family
| Belongs to: |
|---|
| natural cytotoxicity receptor (NCR) family |
Alternative Names
CD336 antigen; CD336; LY95; LY95lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44); lymphocyte antigen 95 (activating NK-receptor; NK-p44); Lymphocyte antigen 95 homolog; natural cytotoxicity triggering receptor 2; Natural killer cell p44-related protein; NCR2; NK cell activating receptor (NKp44); NK cell-activating receptor; NKp44; NK-p44dJ149M18.1
Molecular Weight
Mass (kDA):
30.677 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.1 |
| Sequence: | 6; NC_000006.12 (41335608..41350889) |
Tissue Specificity
Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Neoplasms
- Malignant Neoplasms
- Innate Immune Response
- Leukemia
- Hiv Infections
- Myeloid Leukemia
- Leukemia, Myelocytic, Acute
- Melanoma
- Infective Disorder
- Virus Diseases
- Influenza
- Hepatitis
Interacting Proteins
- PCNA
- TYROBP
Pathways
- Cell Activation
- Immune Response
- Cytokine Production
- Cytolysis
- Pathogenesis
- Secretion
- Cell Killing
- Tropism
- Innate Immune Response
- Viral Replication
- Cell Adhesion
- Gene Silencing
- T Cell Activation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NCR2
bosterbio.com/bosterbio-gene-info-cards/NCR2
References
PMID: 10049942 by Cantoni C., et al. NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily.
PMID: 23958951 by Baychelier F., et al. Identification of a cellular ligand for the natural cytotoxicity receptor NKp44.