NDUFA13 Antibodies

AND NDUFA13 ELISA kits, NDUFA13 Proteins

Many biological assays use antibodies to detect NDUFA13, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDUFA13 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDUFA13 antibodies...

We validate the specificity of these antibodies to NDUFA13 by testing them on tissues known to express NDUFA13 positively and negatively. Browse below to find the NDUFA13 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for NDUFA13? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the NDUFA13 IHC Guide

NDUFA13 Infographic by Boster Bio

All NDUFA13 Products

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Specificity

Applications

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Anti-GRIM19/NDUFA13 Antibody Picoband®

Western blot analysis of GRIM19/NDUFA13 using anti-GRIM19/NDUFA13 antibody (A05981-2)

IHC analysis of GRIM19/NDUFA13 using anti-GRIM19/NDUFA13 antibody (A05981-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05981-2
100 µg/vial

Anti-GRIM19 Rabbit Monoclonal Antibody

Western blot analysis of GRIM19 expression in Ramos cell lysate

IHC analysis of GRIM19/NDUFA13 using anti-GRIM19/NDUFA13 antibody (M05981-1)

Human

IF, IHC, ICC, WB

$370
Cat # M05981-1
100 μl/vial

GRIM19 (NDUFA13) (NM_015965) Human Over-expression Lysate

Human

$628
Cat # LS051079
20 µg, 100 µg

NDUFA13 Overview

Facts about NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13.

NDUFA13 3D structure. Source: alphafold

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (NDUFA13)

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that's believed not to participate in catalysis (PubMed:27626371). Sophisticated I functions in the transport of electrons from NADH to the respiratory chain.

Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1.

Gene Information

Human
Gene Name:	NDUFA13
Uniprot:	Q9P0J0
Entrez:	51079

Family

Belongs to:

complex I NDUFA13 subunit family

Alternative Names

B16.6; CDA016; Cell death regulatory protein GRIM-19; cell death-regulatory protein GRIM19; CI-B16.6; complex I B16.6 subunit; Complex I-B16.6; FLJ58045; FLJ59191; Gene associated with retinoic and IFN-induced mortality 19 protein; Gene associated with retinoic and interferon-induced mortality 19 protein; GRIM-19CGI-39; GRIM19NADH-ubiquinone oxidoreductase B16.6 subunit; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

Molecular Weight

Mass (kDA):
16.698 kDA

Genomic Context


Human

Location:	19p13.11
Sequence:	19; NC_000019.10 (19516225..19528198)

Tissue Specificity

Widely expressed, with highest expression in heart, skeletal muscle, liver, kidney and placenta. In intestinal mucosa, down-regulated in areas involved in Crohn disease and ulcerative colitis.

Subcellular Localizations

Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. Nucleus. Localizes mainly in the mitochondrion (PubMed:12628925). May be translocated into the nucleus upon IFN/RA treatment.

Diseases

Mitochondrial Diseases

Interacting Proteins

HTRA2
NOD2

Pathways

Iron-sulfur Cluster Assembly
Rna Interference

PTMs

Acetylation

Research Areas

Apoptosis
Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDUFA13

References

PMID: 10924506 by Angell J.E., et al. Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach.

PMID: 12163600 by Seo T., et al. Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus interacts with a cell death regulator, GRIM19, and inhibits interferon/retinoic acid-induced cell death.