Nkd2 Antibodies

AND Nkd2 ELISA kits, Nkd2 Proteins

Many biological assays use antibodies to detect Nkd2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nkd2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nkd2 antibodies...

We validate the specificity of these antibodies to Nkd2 by testing them on tissues known to express Nkd2 positively and negatively. Browse below to find the Nkd2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Nkd2 Infographic by Boster Bio

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NKD2 (NM_033120) Human Over-expression Lysate

Human

$960
Cat # LS085409
20 µg, 100 µg

Nkd2 Overview

Facts about Protein naked cuticle homolog 2.

Protein naked cuticle homolog 2 (Nkd2)

Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate another Wnt signaling pathway that controls planar cell polarity.

Required for processing of TGFA and for targeting of TGFA into the basolateral membrane of polarized epithelial cells (By similarity). .

Gene Information

Mouse
Gene Name:	Nkd2
Uniprot:	Q8VE28
Entrez:	72293

Family

Belongs to:

NKD family

Alternative Names

Dvl-binding protein NKD2; hNkd2; naked cuticle homolog 2 (Drosophila); naked cuticle-2; Naked2; naked-2; protein naked cuticle homolog 2

Molecular Weight

Mass (kDA):
51.501 kDA

Genomic Context


Mouse

Location:	13\|13 C1
Sequence:	13;

Tissue Specificity

Expressed in the cecum, colon, esophagus, ileum, jejunum, skin and stomach.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Stomach
Malignant Paraganglionic Neoplasm
Carcinogenesis
Neoplasm Metastasis
Malignant Neoplasm Of Pancreas
Colorectal Cancer
Cell Invasion
Stomach Neoplasms
Malignant Neoplasm Of Breast
Strabismus
Carcinoma

Mammary Neoplasms
Esophageal Neoplasms
Tumor Progression
Malignant Neoplasm Of Lung
Cell Transformation, Neoplastic
Brain Neoplasms
Mutation Abnormality

Pathways

Localization
Segmentation
Cell Proliferation
Cell Migration
Convergent Extension
Somitogenesis
Dna Methylation
Cell Fate Determination
Inflammatory Response
Methylation
Regeneration
Cytokine Production

Tissue Regeneration
Bone Remodeling
Angiogenesis
Pathogenesis
Bone Resorption
Tissue Homeostasis

PTMs

Methylation
Myristoylation

Phosphorylation
Cleavage

Research Areas

Wnt Signaling Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nkd2

References

PMID: 11356022 by Wharton K.A. Jr., et al. Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling.

PMID: 15511637 by Ishikawa A., et al. Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling.