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- Table of Contents
Facts about NLR family pyrin domain-containing protein 2B.
May also play a role in cell cycle progression and apoptotic procedure. .
Human | |
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Gene Name: | NLRP2B |
Uniprot: | P0DMW2 |
Entrez: | 286430 |
Belongs to: |
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No superfamily |
NLR family pyrin domain-containing protein 2B
Mass (kDA):
4.993 kDA
Human | |
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Location: | Xp11.21 |
Sequence: | X; NC_000023.11 (57677067..57680260, complement) |
Expressed in all tissues tested, including spleen, lymph node, thymus, tonsil, peripheral blood leukocyte, bone marrow, liver, heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.
Cytoplasm. Nucleus. Targeted to the nucleus upon TNF-alpha treatment.
PMID: 24871464 by Porter K.A., et al. The CLRX.1/NOD24 (NLRP2P) pseudogene codes a functional negative regulator of NF-kappaB, pyrin-only protein 4.