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- Table of Contents
Facts about NACHT, LRR and PYD domains-containing protein 7.
Inhibits CASP1/caspase-1-Reliant IL1B secretion.
.Human | |
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Gene Name: | NLRP7 |
Uniprot: | Q8WX94 |
Entrez: | 199713 |
Belongs to: |
---|
NLRP family |
NACHT, LRR and PYD domains-containing protein 7
Mass (kDA):
111.807 kDA
Human | |
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Location: | 19q13.42 |
Sequence: | 19; NC_000019.10 (54923509..54965184, complement) |
Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle.
Boster bio has many benefits, including high-affinity primary antibody. Scientists can submit data for species, applications, and special samples. They can also apply to receive credits. These benefits are open to all scientists around the world. You can find out more about Bosterbio by reading the company's history. Here are some benefits to boster bio
Flow cytometry can be used for many scientific purposes. It works by using particles and cells to determine gene expression and cell viability. High-affinity primary antibodies against the NLRP7 marker from Boster Bio can be used in both IHC and WB assays. These antibodies are also highly cited. They are also available in liquid and solid forms.
The primary antibodies are immunoglobulins that bind specifically to their targets. These antibodies' quality is determined by their specificity as well as their affinity. A primary antibody with high affinity will have the highest affinity to the target antigen, while a secondary antibody with low specificity will bind to nonspecific antigens. High-quality primary antibodies are capable in detecting, purifying, and measuring the antigen.
Secondary antibodies can also be used in further studies. Boster Bio provides high-affinity primary antibodies that are specific against the NLRP7 marker as well as other markers. Secondary antibodies can be conjugated to different compounds to perform a specific research. High-affinity primary antibodies can also be used in multiple assays that measure the abundance of particular cell types. This reagent is an excellent investment for researchers from many fields due to its versatility.
Boster Bio NLRP7 antibody tests can detect the protein from different biological samples. Various antibodies are available, which can either be monoclonal or polyclonal. Boster Bio uses rabbit and mouse as the source of their NLRP7 antibody assays. These antibodies react with a number of proteins in human bodies and regulate activation NF-kappa. They also play a role in the regulation caspase-1-dependent Cytokine Processing.
ER is a gene encoding a NLRP3 protein. ER is involved as a mediator of inflammatory diseases like type 2 diabetes, Crohn’s and cancer. NLRP3 can be linked to caspase-8 that is involved in ER damage to the mitochondria. In this study, ER caused ERS was shown by NLRP3 to be recruited to the mitochondria.
Steven Boster is best known for being "he who converts scientific knowledge in the lavatory". His life is full of milestones. Boster, who began his company in 1993 and developed several products in the immunohistochemistry/ELISA fields. His innovations helped Boster to become one the largest Chinese antibody catalog companies. He was also the first person to use trade secrets to create PicoKine(tm), a high-sensitivity ELISA platform.
Don "Steve" Boster, Sr., was a Joliet, IL, native. He passed away in Madison, WI, 6 June 2022, after a long battle to overcome COVID-19. His parents were Donald and Evelyn Meier Boster. He was a Concordia Hall member in Staunton, VA and an Army veteran. His two daughters Crystal and Natosha (and 6 grandchildren) are his surviving family members. Steve is also survived by Jack, Sr., as well as Sandra Boster. He is also survived his sister Tammy, his brother Jonathan, and many nieces or nephews.
PMID: 12019269 by Wang L., et al. PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing.
PMID: 12563287 by Tschopp J., et al. NALPs: a novel protein family involved in inflammation.