Neuropeptide FF receptor 1 (NPFFR1)

Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands.

This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. .