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Nucleoplasmin-2 Antibodies

AND NPM2 ELISA kits, Nucleoplasmin-2 Proteins

Many biological assays use antibodies to detect Nucleoplasmin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nucleoplasmin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nucleoplasmin-2 antibodies...

We validate the specificity of these antibodies to Nucleoplasmin-2 by testing them on tissues known to express NPM2 positively and negatively. Browse below to find the NPM2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NPM2 Infographic by Boster Bio

NPM2 protein infographic

All NPM2 Products

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Product

Figures

Specificity

Applications

Price

Anti-Nucleoplasmin-2 NPM2 Antibody Picoband®

1 Citations 1 Q&As

Anti-NPM2 antibody, PA1991, Western blottingLane 1: HELA Cell LysateLane 2: U87 Cell LysateLane 3: A549 Cell LysateLane 4: SMMC Cell Lysate

Anti-NPM2 antibody, PA1991, Western blottingLane 1: HELA Cell LysateLane 2: U87 Cell LysateLane 3: A549 Cell LysateLane 4: SMMC Cell Lysate

Human

WB

$370
Cat # PA1991
100 μg/vial

Human NPM2 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE

$250
Cat # PROTQ86SE8
Starting from 10ug

NPM2 (NM_182795) Human Over-expression Lysate

NPM2 Human Over-expression Lysates NM_182795

NPM2 Human Over-expression Lysates NM_182795

Human

$628
Cat # LS010361
20 µg, 100 µg

NPM2 Overview

Facts about Nucleoplasmin-2.

NPM2 3D structure

NPM2 3D structure. Source: alphafold

Nucleoplasmin-2 (NPM2)

Core histones chaperone involved in chromatin reprogramming, especially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.

.

Gene Information

Human
Gene Name:	NPM2
Uniprot:	Q86SE8
Entrez:	10361

Gene Information

Family

Belongs to:

nucleoplasmin family

Family

Alternative Names

MGC78655; nucleophosmin/nucleoplasmin 2; nucleoplasmin-2

Molecular Weight

Mass (kDA):
24.152 kDA

Molecular Weight

Genomic Context


Human

Location:	8p21.3
Sequence:	8; NC_000008.11 (22023308..22036908)

Subcellular Localizations

Nucleus. Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm.

Subcellular Localization

Diseases

Malignant Neoplasms
Leukemia, Myelocytic, Acute
Melanocytic Nevus
Myeloid Leukemia
Neoplasms
Melanoma
Leukemia

Female Infertility

Disease

Interacting Proteins

NPM1
NPM3
PLEKHF2
SDCBP2

Interacting Proteins

Pathways

Fertilization
Chromatin Remodeling
Localization
Methylation
Dna Methylation
Sperm Chromatin Decondensation
Oocyte Maturation
Chromatin Assembly
Programmed Cell Death
Gene Silencing
Chromatin Disassembly
Metaphase
Ovulation

Embryo Development
Cellular Response To Ionizing Radiation
Ribosome Biogenesis
Response To Ionizing Radiation
Oocyte Development
Nucleosome Assembly
Translation

Pathways

PTMs

Methylation
Phosphorylation

Deacetylation
Cleavage

Acetylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NPM2

References

PMID: 12714744 by Burns K.H., et al. Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos.

PMID: 17187372 by Frehlick L.J., et al. New insights into the nucleophosmin/nucleoplasmin family of nuclear chaperones.