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- Table of Contents
Facts about Natriuretic peptides B.
Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
| Human | |
|---|---|
| Gene Name: | NPPB |
| Uniprot: | P16860 |
| Entrez: | 4879 |

| Belongs to: |
|---|
| natriuretic peptide family |

BNF; BNP; brain type natriuretic peptide; Gamma-brain natriuretic peptide; natriuretic peptide B; natriuretic peptide precursor B; natriuretic peptides B; natriuretic protein; NPPB
Mass (kDA):
14.726 kDA

| Human | |
|---|---|
| Location: | 1p36.22 |
| Sequence: | 1; NC_000001.11 (11857464..11858945, complement) |
Brain and also in atria, but at much lower levels than ANP.
Secreted.






PMID: 2597152 by Seilhamer J.J., et al. Human and canine gene homologs of porcine brain natriuretic peptide.
PMID: 2522777 by Sudoh T., et al. Cloning and sequence analysis of cDNA encoding a precursor for human brain natriuretic peptide.