Nuclear GTPase SLIP-GC Antibodies

AND NUGGC ELISA kits, Nuclear GTPase SLIP-GC Proteins

Many biological assays use antibodies to detect Nuclear GTPase SLIP-GC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nuclear GTPase SLIP-GC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nuclear GTPase SLIP-GC antibodies...

We validate the specificity of these antibodies to Nuclear GTPase SLIP-GC by testing them on tissues known to express NUGGC positively and negatively. Browse below to find the NUGGC antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NUGGC Infographic by Boster Bio

All NUGGC Products

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C8orf80 (NUGGC) (NM_001010906) Human Recombinant Protein

Coomassie blue staining of purified NUGGC protein

$1062
Cat # PROTQ68CJ6
20 µg

C8orf80 (NUGGC) (NM_001010906) Human Over-expression Lysate

Human

$960
Cat # LS389643
20 µg, 100 µg

NUGGC Overview

Facts about Nuclear GTPase SLIP-GC.

NUGGC 3D structure. Source: alphafold

Nuclear GTPase SLIP-GC (NUGGC)

Nuclear GTPase found in germinal center B-cells, where it could inhibit functioning of the activation-induced cytidine deaminase AICDA (PubMed:19734146). Reduces somatic hypermutation in B-cells which might improve genome stability (By similarity).

Gene Information

Human
Gene Name:	NUGGC
Uniprot:	Q68CJ6
Entrez:	389643

Family

Belongs to:

No superfamily

Alternative Names

Nuclear GTPase SLIP-GC

Molecular Weight

Mass (kDA):
91.132 kDA

Genomic Context


Human

Location:	8p21.1
Sequence:	8; NC_000008.11 (28021964..28084068, complement)

Tissue Specificity

Expressed in germinal center B-cell and in lymphomas derived from germinal center B-cell.

Subcellular Localizations

Nucleus speckle.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NUGGC

References

PMID: 15221005 by Yamada S., et al. Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas.

PMID: 19734146 by Richter K., et al. Speckled-like pattern in the germinal center (SLIP-GC): a nuclear GTPase expressed in activation-induced deaminase-expressing lymphomas and germinal center B cells.