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- Table of Contents
Facts about NACHT domain- and WD repeat-containing protein 1.
| Human | |
|---|---|
| Gene Name: | NWD1 |
| Uniprot: | Q149M9 |
| Entrez: | 284434 |

| Belongs to: |
|---|
| No superfamily |

NACHT domain- and WD repeat-containing protein 1
Mass (kDA):
174.552 kDA

| Human | |
|---|---|
| Location: | 19p13.11 |
| Sequence: | 19; NC_000019.10 (16719526..16817963) |
Expressed at highest levels in prostate, followed by testis, retina, trachea and optic nerve. Also detected in brain, epididymis, lung, vagina and pituitary. In the prostate, tends to be up-regulated during malignant progression compared to normal epithelium (at protein level).
Cytoplasm, cytosol.


PMID: 24681825 by Correa R.G., et al. The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling.