Nucleoredoxin Antibodies

AND Nxn ELISA kits, Nucleoredoxin Proteins

Many biological assays use antibodies to detect Nucleoredoxin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nucleoredoxin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nucleoredoxin antibodies...

We validate the specificity of these antibodies to Nucleoredoxin by testing them on tissues known to express Nxn positively and negatively. Browse below to find the Nxn antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Nucleoredoxin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the NXN Western Blot Guide

Designing an IHC experiment for Nucleoredoxin? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the NXN IHC Guide

Nxn Infographic by Boster Bio

All Nxn Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-NXN/NRX Antibody Picoband®

Western blot analysis of NXN/NRX using anti-NXN/NRX antibody (A08028-1)

IHC analysis of NXN/NRX using anti-NXN/NRX antibody (A08028-1)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A08028-1
100 μg/vial

NXN (NM_022463) Human Over-expression Lysate

Human

$960
Cat # LS064359
20 µg, 100 µg

NXNL2 (NM_145283) Human Over-expression Lysate

Human

$628
Cat # LS158046
20 µg, 100 µg

TXNL6 (NXNL1) (NM_138454) Human Over-expression Lysate

Human

$628
Cat # LS115861
20 µg, 100 µg

Nxn Overview

Facts about Nucleoredoxin.

Nucleoredoxin (Nxn)

Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 from the BCR(KLHL12) complicated. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A).

Gene Information

Mouse
Gene Name:	Nxn
Uniprot:	P97346
Entrez:	18230

Family

Belongs to:

nucleoredoxin family

Alternative Names

EC 1.8.1.8; NRN; NRX; NRXFLJ12614; nucleoredoxin 1; Nucleoredoxin; NXN; TRG-4

Molecular Weight

Mass (kDA):
48.344 kDA

Genomic Context


Mouse

Location:	11 B5\|11 45.92 cM
Sequence:	11;

Tissue Specificity

Widely expressed with higher expression in testis and skin.

Diseases

Hypertensive Disease
Neoplasms
Neoplasm Recurrence, Local
Neurodegenerative Disorders
Malignant Neoplasm Of Breast
Heart Failure
Dehydration
Leukopenia
Stomatitis
Nausea
Systemic Infection
Pyotraumatic Dermatitis

Malignant Neoplasms
Headache
Cardiotoxicity
Convulsions
Mammary Neoplasms
Cerebral Hemorrhage
Vomiting

Pathways

Conjugation

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nxn

References

PMID: 9119370 by Kurooka H., et al. Cloning and characterization of the nucleoredoxin gene that encodes a novel nuclear protein related to thioredoxin.

PMID: 15670764 by Babaya N., et al. Susceptibility to streptozotocin-induced diabetes is mapped to mouse chromosome 11.