Nephronectin Antibodies

AND Npnt ELISA kits, Nephronectin Proteins

Many biological assays use antibodies to detect Nephronectin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nephronectin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nephronectin antibodies...

We validate the specificity of these antibodies to Nephronectin by testing them on tissues known to express Npnt positively and negatively. Browse below to find the Npnt antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Npnt Infographic by Boster Bio

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Npnt Overview

Facts about Nephronectin.

Nephronectin (Npnt)

Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha- 8/beta-1 that is vital for kidney development.

May also play a role in the development and function of various cells, regulating cell adhesion, spreading and survival through the binding of several integrins. .

Gene Information

Mouse
Gene Name:	Npnt
Uniprot:	Q91V88
Entrez:	114249

Family

Belongs to:

nephronectin family

Alternative Names

EGFL6L; Nctn; Nephronectin; NPNT; POEM

Molecular Weight

Mass (kDA):
61.49 kDA

Genomic Context


Mouse

Location:	3\|3 G3
Sequence:	3;

Tissue Specificity

Expressed in kidney (at protein level).

Diseases

Kidney Tubular Necrosis, Acute
Lung Diseases
Carcinoma, Papillary
Acute Kidney Injury
Carcinoma
Lung Diseases, Obstructive
Injury To Kidney
Chronic Obstructive Airway Disease
Malignant Neoplasms

Endocardial Cushion Defects
Papillary Thyroid Carcinoma
Malignant Neoplasm Of Thyroid
Renal Tubular Necrosis

Pathways

Regeneration
Osteoblast Differentiation
Reverse Transcription
Leaflet Formation
Osteoblast Development
Heart Development
Limb Development

Kidney Morphogenesis

PTMs

Disulfide bond

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Npnt

References

PMID: 11546798 by Morimura N., et al. Molecular cloning of POEM: a novel adhesion molecule that interacts with alpha8beta1 integrin.

PMID: 11470831 by Brandenberger R., et al. Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney.