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- Table of Contents
Natriuretic peptides A Antibodies
AND NPPA ELISA kits, Natriuretic peptides A Proteins
Many biological assays use antibodies to detect Natriuretic peptides A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Natriuretic peptides A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Natriuretic peptides A antibodies...
Designing a Western blot for Natriuretic peptides A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the NPPA Western Blot GuideNPPA Infographic by Boster Bio
All NPPA Products
Product
Figures
Specificity
Applications
Price
Anti-ANP/Nppa Antibody Picoband®
2 Citations
Mouse, Rat
ELISA, IHC, WB
$370
Cat # A01318-1
100 μg/vial
Cat # A01318-1
100 μg/vial
Human
ELISA
$499
Cat # EK1627
96 wells/kit, with removable strips.
Cat # EK1627
96 wells/kit, with removable strips.
NPPA Overview
Facts about Natriuretic peptides A.
Natriuretic peptides A (NPPA)
Hormone playing an important role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Plays a role in female pregnancy by encouraging trophoblast invasion and spiral artery remodeling in uterus.
Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Gene Information
| Human | |
|---|---|
| Gene Name: | NPPA |
| Uniprot: | P01160 |
| Entrez: | 4878 |
Family
| Belongs to: |
|---|
| natriuretic peptide family |
Alternative Names
ANF; ANP; ANPatriopeptin; ATFB6; atrial natriuretic factor; Atrial Natriuretic Peptide; Cardionatrin; CDD-ANF; natriuretic peptide A; natriuretic peptide precursor A; NPPA; PND; PNDcardionatrin; prepronatriodilatin
Molecular Weight
Mass (kDA):
16.396 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.22 |
| Sequence: | 1; NC_000001.11 (11845709..11847783, complement) |
Subcellular Localizations
Secreted.
Diseases
- Heart Failure
- Hypertensive Disease
- Hypertrophy
- Cardiac Hypertrophy
- Heart Diseases
- Congenital Heart Defects
- Kidney Diseases
- Decompensated Cardiac Failure
- Acute Decompensated Heart Failure
- Myocardial Infarction
- Cerebrovascular Accident
- Atrial Fibrillation
- Cardiac Fibrillation
Interacting Proteins
- MAGEA12
- UBQLN1
Pathways
- Secretion
- Glomerular Filtration
- Pathogenesis
- Excretion
- Heart Development
- Natriuresis
- Localization
- Transport
- Diuresis
- Cell Differentiation
- Cell Proliferation
- Coagulation
- Fertilization
PTMs
- Phosphorylation
- Cleavage
- Nitration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NPPA
bosterbio.com/bosterbio-gene-info-cards/NPPA
References
PMID: 6203042 by Oikawa S., et al. Cloning and sequence analysis of cDNA encoding a precursor for human atrial natriuretic polypeptide.
PMID: 6547996 by Nakayama K., et al. mRNA sequence for human cardiodilatin-atrial natriuretic factor precursor and regulation of precursor mRNA in rat atria.
2 Publications of Boster Natriuretic peptides A Antibodies & ELISA Kits
- PubMed ID: 27343265, Localization of corin and atrial natriuretic peptide expression in human renal s...
- PubMed ID: 24056563, Effect of growth factors (BMP-4/7 & bFGF) on proliferation & osteogenic differen...
*More publications can be found for each product on its corresponding product page