Opticin Antibodies

AND OPTC ELISA kits, Opticin Proteins

Many biological assays use antibodies to detect Opticin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Opticin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Opticin antibodies...

We validate the specificity of these antibodies to Opticin by testing them on tissues known to express OPTC positively and negatively. Browse below to find the OPTC antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OPTC Infographic by Boster Bio

All OPTC Products

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Product

Figures

Specificity

Applications

Price

Anti-Opticin OPTC Antibody

Western blot (WB) analysis of Opticin polyclonal antibody at 1:500 dilution
Lane1:Hela cell lysate
Lane2:Mouse heart tissue lysate
Lane3:Rat heart tissue lysate

Human, Mouse, Rat

$405
Cat # A09717
100ul

Opticin (OPTC) (NM_014359) Human Recombinant Protein

Coomassie blue staining of purified OPTC protein

$1062
Cat # PROTQ9UBM4
20 µg

Opticin (OPTC) (NM_014359) Human Over-expression Lysate

Human

$628
Cat # LS026254
20 µg, 100 µg

Anti-OPTC Antibody Picoband®

Western blot analysis of OPTC using anti-OPTC antibody (A09717-1)

Human, Monkey

ELISA, WB

$370
Cat # A09717-1
100 µg/vial

OPTC Overview

Facts about Opticin.

OPTC 3D structure. Source: alphafold

Opticin (OPTC)

Binds collagen fibrils. .

Gene Information

Human
Gene Name:	OPTC
Uniprot:	Q9UBM4
Entrez:	26254

Family

Belongs to:

small leucine-rich proteoglycan (SLRP) family

Alternative Names

oculoglycan; Oculogylcan; OPT; OPTC; Opticin

Molecular Weight

Mass (kDA):
37.261 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (203494153..203508949)

Tissue Specificity

Retina, iris, ligament, skin and fetal liver.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Retinal Diseases
Tissue Adhesions
Disorder Of Vitreous Humor
Glaucoma, Open-angle
Glaucoma
Primary Open Angle Glaucoma
Hypoxia
Tumor Angiogenesis
Pathologic Neovascularization
Myopia
Severe Myopia
Disorder Of Eye

Adenoma
Vitreous Detachment
Ataxia
Retinal Perforations
Nerve Transections, Optic
Scleral Diseases
Venous Occlusion

Pathways

Pathogenesis
Localization
Angiogenesis
Sulfation
Reverse Transcription
Secretion

Extracellular Matrix Assembly

PTMs

Cleavage

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OPTC

References

PMID: 10636917 by Reardon A.J., et al. Identification in vitreous and molecular cloning of opticin, a novel member of the family of leucine-rich repeat proteins of the extracellular matrix.

PMID: 10837509 by Hobby P., et al. Cloning, modeling, and chromosomal localization for a small leucine- rich repeat proteoglycan (SLRP) family member expressed in human eye.