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- Table of Contents
Facts about Probable tRNA N6-adenosine threonylcarbamoyltransferase.
OSGEP probably plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. .
| Human | |
|---|---|
| Gene Name: | OSGEP |
| Uniprot: | Q9NPF4 |
| Entrez: | 55644 |

| Belongs to: |
|---|
| KAE1 / TsaD family |

EC 3.4.24.57; GCPL1FLJ20411; hOSGEP; KAE1; OSGEP1; O-sialoglycoprotein endopeptidase; probable O-sialoglycoprotein endopeptidase; PRSMG1; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP
Mass (kDA):
36.427 kDA

| Human | |
|---|---|
| Location: | 14q11.2 |
| Sequence: | 14; NC_000014.9 (20446401..20454812, complement) |
Widely expressed at low level. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas.
Cytoplasm. Nucleus.





PMID: 12039036 by Seki Y., et al. Sequencing analysis of a putative human O-sialoglycoprotein endopeptidase gene (OSGEP) and analysis of a bidirectional promoter between the OSGEP and APEX genes.
PMID: 22912744 by Costessi A., et al. The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME.