Ostm1 Antibodies

AND Ostm1 ELISA kits, Ostm1 Proteins

Many biological assays use antibodies to detect Ostm1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ostm1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ostm1 antibodies...

We validate the specificity of these antibodies to Ostm1 by testing them on tissues known to express Ostm1 positively and negatively. Browse below to find the Ostm1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ostm1 Infographic by Boster Bio

All Ostm1 Products

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Specificity

Applications

Price

Anti-OSTM1 Antibody

Western blot analysis of extracts of various cell lines, using OSTM1 antibody at 1:3000 dilution

Human, Mouse, Rat

$405
Cat # A05269
100ul

OSTM1 (NM_014028) Human Over-expression Lysate

Human

$628
Cat # LS028962
20 µg, 100 µg

Anti-OSTM1 Antibody Picoband®

Western blot analysis of OSTM1 using anti-OSTM1 antibody (A05269-1)

IF analysis of OSTM1 using anti-OSTM1 antibody (A05269-1) and anti-Beta Tubulin antibody (M01857-3)

Human

IF, ICC, WB

$370
Cat # A05269-1
100 μg/vial

Ostm1 Overview

Facts about Osteopetrosis-associated transmembrane protein 1.

Osteopetrosis-associated transmembrane protein 1 (Ostm1)

Required for osteoclast and melanocyte maturation and function. .

Gene Information

Mouse
Gene Name:	Ostm1
Uniprot:	Q8BGT0
Entrez:	14628

Family

Belongs to:

OSTM1 family

Alternative Names

GIPN; GLGAIP-interacting protein N terminus; grey-lethal osteopetrosis; HSPC019; OPTB5; osteopetrosis associated transmembrane protein 1; osteopetrosis-associated transmembrane protein 1

Molecular Weight

Mass (kDA):
38 kDA

Genomic Context


Mouse

Location:	10 B2\|10 22.89 cM
Sequence:	10;

Tissue Specificity

Expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Found at lower levels in the thymus, testis, heart and liver.

Diseases

Albers-schonberg Disease
Malignant Paraganglionic Neoplasm
Lysosomal Storage Diseases
Storage Disease
Bone Diseases
Pancytopenia
Atrophy
Genetic Diseases, Inborn
Infantile Malignant Osteopetrosis
Osteosclerosis
Fracture
Nerve Degeneration

Hereditary Diseases
Cerebral Atrophy
Kidney Calculi
Nervousness
Optic Atrophy
Malnutrition

Pathways

Bone Resorption
Transport
Pathogenesis
Endocytosis
Localization
Osteoclast Differentiation
Chloride Transport
Endoderm Formation
Osteoclast Development
Anion Transport

Cell Development
Transepithelial Transport
Osteoclast Maturation
Bone Remodeling
Tissue Homeostasis

PTMs

Glycosylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ostm1

References

PMID: 12627228 by Chalhoub N., et al. Grey-lethal mutation induces severe malignant autosomal recessive osteopetrosis in mouse and human.

PMID: 16525474 by Lange P.F., et al. ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function.