Oxytocin-neurophysin 1 Antibodies

AND OXT ELISA kits, Oxytocin-neurophysin 1 Proteins

Many biological assays use antibodies to detect Oxytocin-neurophysin 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Oxytocin-neurophysin 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Oxytocin-neurophysin 1 antibodies...

We validate the specificity of these antibodies to Oxytocin-neurophysin 1 by testing them on tissues known to express OXT positively and negatively. Browse below to find the OXT antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OXT Infographic by Boster Bio

All OXT Products

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Applications

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Anti-Neurophysin I (K40) OXT Antibody

Western blot (WB) analysis of Neurophysin I (K40) pAb at 1:500 dilution
Lane1:A549 whole cell lysate(20ug)
Lane2:SGC7901 whole cell lysate(40ug)
Lane3:3T3-L1 whole cell lysate(40ug)
Lane4:H9C2 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Neurophysin I (K40) pAb in paraffin-embedded human brain tissue

Human, Mouse, Rat

IHC, WB

$405
Cat # A01545
100ul

Anti-Oxytocin neurophysin 1 (OXT) Mouse Monoclonal Antibody [Clone ID: OTI5G4]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OXT (Right lane) cDNA for 48 hrs and lysed

Human, Mouse, Rat

$523
Cat # M01545
100 µl

Anti-OXT Antibody (Monoclonal, 32O19)

Human, Mouse, Rat

IF, IHC, WB

$370
Cat # M01545-1
100 μl/vial

OXT Overview

Facts about Oxytocin-neurophysin 1.

OXT 3D structure. Source: alphafold

Oxytocin-neurophysin 1 (OXT)

Neurophysin 1 specifically binds oxytocin. .

Gene Information

Human
Gene Name:	OXT
Uniprot:	P01178
Entrez:	5020

Family

Belongs to:

vasopressin/oxytocin family

Alternative Names

MGC126890; MGC126892; Neurophysin I; OT; OT-NPI; OXT; Oxytocin; oxytocin, prepro- (neurophysin I); oxytocin, prepropeptide; oxytocin-neurophysin 1; oxytocin-neurophysin I, preproprotein

Molecular Weight

Mass (kDA):
12.722 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (3068871..3072517)

Subcellular Localizations

Secreted.

Diseases

Pituitary Diseases
Nervousness
Stress, Psychological
Anxiety Disorders
Autistic Disorder
Physiological Stress
Pain
Depressive Disorder
Dehydration
Diabetes Mellitus
Mental Disorders
Alzheimer's Disease

Autism Spectrum Disorders
Morphine Dependence
Obesity
Bradycardia
Hyperphagia
Substance Withdrawal Syndrome

Pathways

Secretion
Lactation
Parturition
Reflex
Maternal Behavior
Social Behavior
Localization
Cognition
Milk Ejection
Aging
Innervation
Swimming

Transport
Luteolysis
Gastric Emptying
Hormone Secretion
Synaptic Transmission
Mating
Response To Stress

PTMs

Phosphorylation
Glycosylation
Cleavage

Acetylation
Dephosphorylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OXT

References

PMID: 3768139 by Rehbein M., et al. The neurohypophyseal hormones vasopressin and oxytocin. Precursor structure, synthesis and regulation.

PMID: 2991279 by Sausville E., et al. The human vasopressin gene is linked to the oxytocin gene and is selectively expressed in a cultured lung cancer cell line.