P2X purinoceptor 4 Antibodies

AND P2RX4 ELISA kits, P2X purinoceptor 4 Proteins

Many biological assays use antibodies to detect P2X purinoceptor 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with P2X purinoceptor 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop P2X purinoceptor 4 antibodies...

We validate the specificity of these antibodies to P2X purinoceptor 4 by testing them on tissues known to express P2RX4 positively and negatively. Browse below to find the P2RX4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for P2X purinoceptor 4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the P2RX4 Western Blot Guide

P2RX4 Infographic by Boster Bio

All P2RX4 Products

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Specificity

Applications

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Anti-P2X4/P2RX4 Antibody Picoband®

Western blot analysis of P2X4/P2RX4 using anti-P2X4/P2RX4 antibody (A04715-2)

Human

ELISA, WB

$370
Cat # A04715-2
100 μg/vial

Anti-P2RX4 Antibody Picoband®

Western blot analysis of P2RX4 using anti-P2RX4 antibody (PB9304)

Human, Monkey, Mouse, Rat

$370
Cat # PB9304
100 μg/vial

P2RX4 (NM_002560) Human Over-expression Lysate

Human

$628
Cat # LS005025
20 µg, 100 µg

P2RX4 Overview

Facts about P2X purinoceptor 4.

P2RX4 3D structure. Source: alphafold

P2X purinoceptor 4 (P2RX4)

Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin.

Gene Information

Human
Gene Name:	P2RX4
Uniprot:	Q99571
Entrez:	5025

Family

Belongs to:

P2X receptor family

Alternative Names

ATP receptor; ATP-gated cation channel protein; P2RX4; P2X purinoceptor 4; P2X4; P2X4P2X receptor, subunit 4; P2X4R; purinergic receptor P2X, ligand-gated ion channel, 4; Purinergic receptor; purinoceptor P2X4

Molecular Weight

Mass (kDA):
43.369 kDA

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (121210096..121234106)

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Pain
Neuralgia
Nerve Damage
Nervousness
Inflammation
Peripheral Nerve Injuries
Hyperalgesia, Tactile
Peripheral Neuropathy
Heart Failure
Chronic Pain
Hyperalgesia
Hypertensive Disease

Malignant Neoplasms
Hypertrophy
Hyperalgesias, Mechanical
Brain Injuries
Diabetes Mellitus
Infarction
Myocardial Infarction

Interacting Proteins

KRTAP5-9
NOTCH2NL
PIH1D3

Pathways

Localization
Response To Atp
Secretion
Hypersensitivity
Synaptic Transmission
Endocytosis
Transport
Vasodilation
Pathogenesis
Clathrin-mediated Endocytosis
Cell Activation
Inflammatory Response
Membrane Depolarization

Reverse Transcription
Translation
Phagocytosis
Bioluminescence
Cell Proliferation
Innervation
Bone Resorption

PTMs

Phosphorylation
Biotinylation

Cleavage
Glycosylation

Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/P2RX4

References

PMID: 9016352 by Garcia-Guzman M., et al. Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue.

PMID: 10515189 by Carpenter D., et al. Site-specific splice variation of the human P2X4 receptor.