PAICS Antibodies

AND PAICS ELISA kits, PAICS Proteins

Many biological assays use antibodies to detect PAICS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PAICS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PAICS antibodies...

We validate the specificity of these antibodies to PAICS by testing them on tissues known to express PAICS positively and negatively. Browse below to find the PAICS antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PAICS Infographic by Boster Bio

All PAICS Products

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Figures

Specificity

Applications

Price

Anti-Multifunctional protein ADE2 PAICS Antibody

Western blot analysis of extracts of various cell lines, using PAICS antibody at 1:1000 dilution

Immunofluorescence analysis of U2OS cells using PAICS antibody

Human, Rat

IF, ICC, WB

$405
Cat # A07031
100ul

PAICS (NM_001079524) Human Recombinant Protein

Coomassie blue staining of purified PAICS protein

$1062
Cat # PROTP22234
20 µg

Anti-PAICS Mouse Monoclonal Antibody [Clone ID: OTI1B4]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PAICS (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (10ug) from 5 different cell lines by using anti-PAICS monoclonal antibody at 1:200 dilution

HEK293T cells transfected with either PAICS (Myc-DDK-tagged) overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PAICS antibody (M07031)

Human, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M07031
100 µl

PAICS (NM_001079525) Human Over-expression Lysate

PAICS Human Over-expression Lysates NM_001079524

Human

$960
Cat # LS010606
20 µg, 100 µg

Anti-PAICS Antibody Picoband®

Western blot analysis of PAICS using anti-PAICS antibody (A07031-1)

Flow Cytometry analysis of PC-3 cells using anti-PAICS antibody (A07031-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A07031-1
100 µg/vial

PAICS Overview

Facts about Multifunctional protein ADE2.

PAICS 3D structure. Source: alphafold

Multifunctional protein ADE2 (PAICS)

Gene Information

Human
Gene Name:	PAICS
Uniprot:	P22234
Entrez:	10606

Family

Belongs to:

No superfamily

Alternative Names

ADE2; AIR carboxylase; AIRCADE2H1; DKFZp781N1372; MGC1343; MGC5024; multifunctional protein ADE2; PAIS; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazolesuccinocarboxamide synthetase; SAICAR synthetase

Molecular Weight

Mass (kDA):
47.079 kDA

Genomic Context


Human

Location:	4q12
Sequence:	4; NC_000004.12 (56435749..56464578)

Diseases

Malignant Neoplasms
Prion Diseases
Glioblastoma Multiforme
Cell Transformation, Neoplastic
Malignant Squamous Cell Neoplasm
Microphthalmos
Lung Neoplasms
Non-small Cell Lung Carcinoma
Schizophrenia
Glioblastoma
Tissue Adhesions

Acute Lymphocytic Leukemia
Malignant Neoplasm Of Lung
Carcinoma
Carcinogenesis
Neoplasms
Leukemia

Interacting Proteins

FXR2
L3MBTL2
LNX1
NUDT18

Pathways

Cell Cycle
Cell Adhesion
Response To Risperidone
Programmed Cell Death
Cell Death
S Phase
Aging

Pigmentation

PTMs

Acetylation

Phosphoprotein

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAICS

References

PMID: 2253271 by Minet M., et al. Cloning and sequencing of a human cDNA coding for a multifunctional polypeptide of the purine pathway by complementation of the ade2-101 mutant in Saccharomyces cerevisiae.

PMID: 17224163 by Li S.-X., et al. Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis.